Element- and isotope-specific detection for high-performance liquid chromatography using chemical reaction interface mass spectrometry.
Element- and isotope-specific detection for high-performance liquid chromatography using chemical reaction interface mass spectrometry.
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使用化学反应界面质谱进行高效液相色谱的元素和同位素特异性检测。
DOI：
10.1016/0021-9673(95)01279-6
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Abramson,FP
中科院分区：
文献类型：
--
作者：
McLean,M;Vestal,ML;Teffera,Y;Abramson,FP
我们开发了一种结合高效液相色谱（HPLC）和化学反应界面质谱（CRIMS）的方法，通过使用韦斯特克通用接口（UI）。该界面提供了CRIMS工艺所需的极高程度的溶剂去除。在此过程中，我们生产了一种HPLC检测器，能够进行元素和同位素选择性分析，其检测特性具有：线性、结构独立、灵敏、选择性、全面和灵活。仪器的特点和它的性能进行了说明。
We have developed a combination of high-performance liquid chromatography (HPLC) and the chemical reaction interface mass spectrometry (CRIMS) method by using a Vestec Universal Interface (UI). This interface provides the extremely high degree of solvent removal that the CRIMS process requires. In doing so, we have produced an HPLC detector with the ability to carry out element- and isotope-selective analyses with detection that is inherently: linear, structure-independent, sensitive, selective, comprehensive and flexible. The characteristics of the instrumentation and its performance are described.