The AIDS and Cancer Specimen Resource
The AIDS and Cancer Specimen Resource
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DOI：
10.1007/978-1-59745-423-0_8
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发表时间：
2011-01-01
期刊：
影响因子：
--
通讯作者：
Garcia, Debra L.
中科院分区：
文献类型：
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作者：
Ayers, Leona W.;Silver, Sylvia;Garcia, Debra L.
艾滋病和癌症标本资源(ACSR)是美国国家癌症研究所(NCI)(艾滋病毒和艾滋病恶性肿瘤办公室主任办公室(OHAM))和美国地区性财团、加州大学旧金山分校(西海岸)、乔治华盛顿大学(东海岸)和俄亥俄州立大学(中部地区)之间的合作协议。ACSR的主要目标是收集、保存和分发艾滋病毒相关组织和生物液以及临床数据给合格的调查人员，重点是艾滋病毒/艾滋病相关的恶性肿瘤。ACSR生物信息库拥有超过265,000份人类艾滋病毒阳性和对照样本，来自39种加工类型、16种标本类型和52种解剖部位类型。这些感染艾滋病毒的生物液体和组织可免费提供给获得资助的经批准的研究人员。可提供技术支持，如组织中的艾滋病毒DNA鉴定和组织微阵列(TMA)块，以协助经批准的调查人员。如果目前库存的材料不能满足研究需要，可以通过ACSR合作安排来满足。那些参与ACSR的人预计将与科学界分享他们的研究成果。在国家和国际科学会议上发表了约117份摘要/海报和讲台报告，出版了94份出版物(截至2010年)。研究人员可以浏览ACSR网站http://acsr.ucsf.edu上的生物标记物，以支持他们的科学倡议，包括基础、翻译、生物标记物发现和分子流行病学研究。
The AIDS and Cancer Specimen Resource (ACSR) is a cooperative agreement among the United States National Cancer Institute (NCI) (Office of the Director, Office of HIV and AIDS Malignancy (OHAM)) and regional US consortia, University of California, San Francisco (West Coast), George Washington University (East Coast), and The Ohio State University (Mid-Region). The ACSR's main objective is to collect, preserve, and disperse HIV-related tissues and biologic fluids along with clinical data to qualified investigators with a focus on HIV/AIDS-related malignancies. The ACSR biorepository has more than 265,000 human HIV-positive and control samples available from 39 processing types, 16 specimen types, and 52 anatomical site types. These HIV-infected biological fluids and tissues arc made available to funded approved investigators at no fee. Technical support such as HIV DNA identification in tissues and tissue microarray (TMA) blocks are available to assist approved investigators. Research needs may be filled through ACSR cooperative arrangements when not met by currently banked material. Those participating with the ACSR are expected to share their research findings with the scientific community. Some 117 abstract/poster and podium reports at national and international scientific meetings and 94 publications have been contributed to the scientific literature (as of 2010). Investigators can browse the ACSR Internet site at http://acsr.ucsf.edu for biospecimens to support their scientific initiatives, including basic, translational, biomarker discovery, and molecular epidemiology studies.