Geriatric assessment in surgical oncology: a systematic review.

Geriatric assessment in surgical oncology: a systematic review.
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DOI:
10.1016/j.jss.2014.07.004
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发表时间:
2015-01
影响因子:
2.2
通讯作者:
Smith, Angela B.
Smith, Angela B.
中科院分区:
医学3区
文献类型:
--
作者:
Feng, Megan A.;McMillan, Daniel T.;Crowell, Karen;Muss, Hyman;Nielsen, Matthew E.;Smith, Angela B.

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综合老年评估(CGA)已发展成为一个重要的预后工具,风险分层的老年人,最近已被应用到外科领域。在这篇系统性综述中,我们研究了CGA成分作为接受大型肿瘤手术的老年患者不良结局预测因子的实用性。在MEDLINE、Embase和科克伦图书馆中检索前瞻性研究,研究CGA的组成部分与接受择期肿瘤手术的老年患者的特定结局之间的关系。结果参数包括术后30天并发症、死亡率和出院至非家庭机构。初步检索确定了178篇潜在相关文章,其中6项研究符合纳入标准。工具性日常生活活动(IADL)、ADL、疲劳、认知、虚弱和认知障碍的缺陷与术后并发症的增加相关。未发现CGA预测术后死亡率的因素,而虚弱、IADL缺陷和抑郁可预测出院至非家庭机构。在各种外科肿瘤人群和癌症类型中,CGA的组成部分似乎可以预测术后并发症和出院到非家庭机构。这些结果表明,在老年外科肿瘤人群中,应将重点老年评估作为常规术前护理的一部分。
The comprehensive geriatric assessment (CGA) has developed as an important prognostic tool to risk stratify older adults and has recently been applied to the surgical field. In this systematic review, we examined the utility of CGA components as predictors of adverse outcomes among geriatric patients undergoing major oncologic surgery. MEDLINE, Embase, and the Cochrane Library were searched for prospective studies examining the association of components of the CGA with specific outcomes among geriatric patients undergoing elective oncologic surgery. Outcome parameters included 30-day post-operative complications, mortality, and discharge to a non-home institution. The initial search identified 178 potentially relevant articles, with six studies meeting inclusion criteria. Deficiencies in instrumental activities of daily living (IADLs), ADLs, fatigue, cognition, frailty, and cognitive impairment were associated with increased post-operative complications. No CGA predictors were identified for post-operative mortality while frailty, deficiencies in IADLs, and depression predicted discharge to a non-home institution. Across a variety of surgical oncologic populations and cancer types, components of the CGA appear to be predictive of post-operative complications and discharge to a non-home institution. These results argue for inclusion of focused geriatric assessments as part of routine pre-operative care in the geriatric surgical oncology population.
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