Incidence of hypertension and non-insulin dependent diabetes mellitus and associated risk factors in a rapidly developing Caribbean community: The St James survey, Trinidad
Incidence of hypertension and non-insulin dependent diabetes mellitus and associated risk factors in a rapidly developing Caribbean community: The St James survey, Trinidad
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DOI：
10.1136/jech.50.5.497
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发表时间：
1996-10-01
影响因子：
6.3
通讯作者：
Beckles, GLA
中科院分区：
文献类型：
--
作者：
Miller, GJ;Maude, GH;Beckles, GLA
目的：比较一个快速发展社区中高血压和非胰岛素依赖型糖尿病的发病率与种族和其他特征的关系。设计-对整个社区进行为期五年的前瞻性监测。受试者：2491名年龄在35岁至69岁之间的男性和女性（79%应答），非洲人、印度人和“其他”（主要是非裔欧洲人）后裔。结果：在监测期间，男女空腹血糖浓度和体重指数（BMI）长期升高，男女收缩压长期明显降低。高血压发病率在种族间无显著差异，男性为每1000人年33 - 41人，女性为每1000人年27 - 32人。在男性中，印度人的糖尿病发病率（每1000人年）为24例，显著高于非洲人（13例）和其他人群（11例）。女性糖尿病发病率在印度（23例）和非洲（14例）与男性相似，但在其他国家是男性的两倍（21例）。在两性中，体重增加是高血压的重要危险因素，而糖尿病的风险随着基线BMI的增加而增加。印度男性患糖尿病的风险增加与基线BMI和血糖无关。结论：除了印度人患糖尿病的风险增加外，特立尼达的种族对高血压和糖尿病的发病率没有显著影响。男女血糖和男性BMI的长期升高可能导致该社区冠心病死亡率的同时升高。
Objective - To compare the incidence rates of hypertension and non-insulin dependent diabetes mellitus in relation to ethnicity and other characteristics in a rapidly developing community.Design - Prospective surveillance of a total community for five years.Subjects - Cohort of 2491 men and women aged 35 to 69 years (79% response), of African, Indian and 'other' (mainly Afro-European) descent.Results - During surveillance, secular increases occurred in fasting blood glucose concentrations in both sexes and in body mass index (BMI) in men with apparent secular reductions in systolic blood pressure in both sexes. Incidence rates of hypertension did not differ significantly with ethnicity, ranging between 33 and 41 per 1000 person-years in men and between 27 and 32 per 1000 person-years in women. In men, the incidence of diabetes (per 1000 person-years) in Indians (24) was significantly higher than in Africans (13) and others (11). In women, the diabetic incidence was similar to that for men in Indians (23) and Africans (14), but in others was twice that in men (21). In both sexes, weight gain was an important risk factor for hypertension, whereas risk of diabetes increased with BMI at baseline. The increased risk of diabetes in Indians among men was independent of baseline BMI and blood glucose.Conclusion - Apart from the increased risk of diabetes in Indians, ethnicity had no significant influence on incidence rates of hypertension and diabetes in Trinidad. Secular increases in blood glucose in both sexes and in BMI in men probably contributed to the concurrent increase in mortality from coronary heart disease in this community.