Social influences on cortisol and behavioral responses of preweaning, periadolescent, and adult guinea pigs
Social influences on cortisol and behavioral responses of preweaning, periadolescent, and adult guinea pigs
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DOI：
10.1016/s0031-9384(02)00712-6
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发表时间：
2002-06-01
影响因子：
2.9
通讯作者：
Wilson, SE
中科院分区：
文献类型：
--
作者：
Hennessy, MB;O'Leary, SK;Wilson, SE
在许多物种中，依恋图形的存在可以降低下丘脑-垂体-肾上腺（HPA）反应。在豚鼠中，母亲在断奶之前和之后都会降低幼崽的HPA升高。最近，一个陌生的女性也被发现，以减少断奶后豚鼠的HPA反应。本研究评估了不熟悉的女性的影响的特异性和个体发育过程。实验1发现，一个不熟悉的成年男性并没有减少皮质醇反应的青少年期受试者在新奇的曝光。实验2表明，不熟悉的女性的影响是存在的，早在第二周的生活。实验3发现，无论是陌生的成年女性还是男性，都不会影响成年豚鼠的皮质醇反应。在所有的实验中，母亲都降低了后代的皮质醇水平。缓冲皮质醇反应的能力不能用受试者从刺激动物那里得到的激动行为的数量来解释。结果表明，母亲豚鼠有一个持久的能力，以缓冲HPA反应在她的发展中的后代，在至少很大一部分的时间，母亲可以缓和皮质醇的反应，她的年轻，所以也可以一个不熟悉的成年女性，但不是一个不熟悉的成年男性，以及社会合作伙伴的能力，以缓和HPA活动是不容易预测的行为相互作用。(C)2002年爱思唯尔科技有限公司All rights reserved.
in various species, the presence of an attachment figure can reduce hypothalamic-pituitary-adrenal (HPA) responses. in the guinea pig, the mother reduces HPA elevations of her young both prior to and following weaning. Recently, an unfamiliar female was also found to reduce the HPA responses of postweaning guinea pigs. The present study evaluated the specificity and ontogenetic course of the effect of the unfamiliar female. Experiment 1 found that an unfamiliar adult male did not reduce the cortisol response of periadolescent subjects during novelty exposure. Experiment 2 showed that the effect of the unfamiliar female was present as early as the second week of life. Experiment 3 found that neither an unfamiliar adult female nor male affected the cortisol response in adult guinea pigs. In all experiments, the mother reduced the cortisol elevations of her offspring. The ability to buffer the cortisol response could not be explained by the amount of agonistic behavior subjects received from the stimulus animals. Results indicate that the mother guinea pig has a persisting ability to buffer HPA responses in her developing offspring; that during at least a large portion of the time that the mother can moderate the cortisol response of her young, so too can an unfamiliar adult female, but not an unfamiliar adult male; and that the ability of social partners to moderate HPA activity is not readily predictable from behavioral interactions. (C) 2002 Elsevier Science Inc. All rights reserved.