Physical activity, obesity, and cognitive impairment among women with systemic lupus erythematosus
Physical activity, obesity, and cognitive impairment among women with systemic lupus erythematosus
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DOI：
10.1002/acr.21587
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发表时间：
2012-04-01
影响因子：
4.7
通讯作者：
Criswell, Lindsey A.
中科院分区：
文献类型：
--
作者：
Katz, Patricia;Julian, Laura;Criswell, Lindsey A.
目的探讨肥胖、缺乏运动与系统性红斑狼疮(SLE)患者认知功能障碍的关系。采用双X射线骨密度仪(DXA)对138例系统性红斑狼疮(SLE)患者进行身体成分测定。肥胖的定义是身体脂肪的总百分比。体力活动是通过自我报告的国际体力活动问卷确定的；不活动的定义是每周花费600英镑的代谢物当量分钟。认知功能用12指数神经心理成套测验进行评估。损害被定义为年龄调整后的Z分数
Objective To examine relationships of obesity and physical inactivity to cognitive impairment in women with systemic lupus erythematosus (SLE).Methods. Body composition was measured with dual x-ray absorptiometry (DXA) for 138 women with SLE. Obesity was defined by total percent body fat. Physical activity was ascertained with the self-reported International Physical Activity Questionnaire; inactivity was defined as expenditure of < 600 metabolic equivalent minutes/week. Cognitive function was assessed with a 12-index neuropsychological battery. Impairment was defined as age-adjusted Z scores