Dissociable contributions of prefrontal and parietal cortices to response selection
Dissociable contributions of prefrontal and parietal cortices to response selection
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DOI：
10.1006/nimg.2002.1252
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发表时间：
2002-11-01
期刊：
影响因子：
5.7
通讯作者：
Gabrieli, JDE
中科院分区：
文献类型：
--
作者：
Bunge, SA;Hazeltine, E;Gabrieli, JDE
在特定情况下从可能的反应中做出选择的能力是人类认知的核心。本研究的目的是区分代表候选反应的大脑区域和在竞争性反应选择之间进行选择的大脑区域。在10名健康成年人执行一项用于检查反应竞争的任务时，获得了与事件相关的fMRI数据：埃里克森侧卫任务。左顶叶皮层被两种操作中的任何一种激活，增加了维持可能反应表征的需要。相反，外侧前额叶。而吻侧前扣带皮层则特别需要在竞争性反应中进行选择。这些发现支持了这样一种观点，即在习得性刺激-反应关联的基础上，顶叶皮层和前额叶皮层参与激活可能的反应。当需要在相互竞争的反应之间做出选择时，大脑皮层就会被激活。(C) 2002 Elsevier Science （USA）。
The ability to select between possible responses to a given situation is central to human cognition. The goal of this study was to distinguish between brain areas representing candidate responses and areas selecting between competing response alternatives. Event-related fMRI data were acquired while 10 healthy adults performed a task used to examine response competition: the Eriksen flanker task. Left parietal cortex was activated by either of two manipulations that increased the need to maintain a representation of possible responses. In contrast, lateral prefrontal. and rostral anterior cingulate cortices were specifically engaged by the need to select among competing response alternatives. These findings support the idea that parietal cortex is involved in activating possible responses on the basis of learned stimulus-response associations, and that prefrontal. cortex is recruited when there is a need to select between competing responses. (C) 2002 Elsevier Science (USA).