FLATTENING OF PROTON DOSE DISTRIBUTIONS FOR LARGE FIELD RADIO THERAPY
FLATTENING OF PROTON DOSE DISTRIBUTIONS FOR LARGE FIELD RADIO THERAPY
复制标题
DOI：
10.1118/1.594317
复制
发表时间：
1977-01-01
期刊：
影响因子：
--
通讯作者：
SISTERSON J M
中科院分区：
文献类型：
--
作者：
KOEHLER A M;SCHNEIDER R J;SISTERSON J M
描述了在大面积上获得展平的带电粒子剂量分布的方法。详细讨论了哈佛用于质子放射治疗的系统。它是对常规多次散射技术的一种扩展，包括阻挡一些中心峰，然后再散射以填充轮廓，从而得到直径达30厘米的平坦分布。在癌症患者中，异常长的源皮距（4.6米源皮距）加上多次散射产生的小的横向扩散（2毫米均方根），导致在整个治疗体积内射束的发散很小。
Methods for obtaining flattened charged-particle dose distributions over large areas are described. The system being used at Harvard for proton radiotherapy is discussed in detail. It is an extension of usual multiple-scattering techniques to include blocking out some of the central peak, followed by rescattering to fill in the profile, resulting in flat distributions up to 30 cm in diameter. The unusually long source-to-skin distance (4.6-m SSD) plus the small lateral spread (2 mm rms [root-mean-square]) from multiple scattering in the cancer patient results in little divergence of the beam throughout the treatment volume.