CVD risk among men participating in the National Health and Nutrition Examination Survey (NHANES) from 2001 to 2010: differences by sexual minority status.
CVD risk among men participating in the National Health and Nutrition Examination Survey (NHANES) from 2001 to 2010: differences by sexual minority status.
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DOI：
10.1136/jech-2013-202658
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发表时间：
2013-09
影响因子：
6.3
通讯作者：
Bowen DJ
中科院分区：
文献类型：
--
作者：
Farmer GW;Bucholz KK;Flick LH;Burroughs TE;Bowen DJ
最近的研究表明，与异性恋女性相比，性少数女性患心血管疾病（CVD）的风险更高；然而，针对性少数男性 (SMM) 的 CVD 风险研究很少。本研究旨在确定 SMM 的 CVD 风险是否存在差异，以及 SMM 亚组的 CVD 风险是否一致。这项研究利用了 2001 年至 2010 年全国健康和营养检查调查 (NHANES) 的公开数据。CVD 风险是使用弗雷明汉一般 CVD 风险评分计算的，并以参与者的血管年龄和实际年龄的比率进行计算。研究了异性恋和 SMM 之间以及 SMM 亚组内这一比例的差异。 SMM 的血管系统比异性恋者平均年轻 4.0% (95% CI = -7.5%, -0.4%)；然而，对教育程度和吸毒史进行调整后，这种差异在统计上并不显着。对 SMM 亚组的分析显示，与异性恋男性相比，双性恋男性的 CVD 风险增加，而男同性恋和有同性恋经历的异性恋男性的 CVD 风险降低。在调整教育程度和吸毒史后，只有双性恋和有同性恋经历的异性恋男性的 CVD 风险仍然存在差异。与异性恋男性相比，SMM 亚群患 CVD 的风险更高，而且这种风险的增加不能完全归因于人口特征的差异或不良健康行为。
Recent research indicates sexual minority women are at increased risk for cardiovascular disease (CVD) compared to Heterosexual women; however, few studies of CVD risk exist for sexual minority men (SMM). This study aimed to determine whether disparities in CVD risk exist for SMM and if CVD risk is consistent across subgroups of SMM. This study utilized publicly available data from the National Health and Nutrition Examination Survey (NHANES), pooled from 2001 to 2010. CVD risk was calculated using the Framingham General CVD Risk Score and operationalized as the ratio of a participant’s vascular and chronological age. Differences in this ratio were examined between Heterosexual and SMM as a whole, and within subgroups of SMM. SMM had vascular systems that were on average 4.0% (95% CI = −7.5%, −0.4%) younger than their Heterosexual counterparts; however, adjustment for education and history of hard drug use rendered this difference statistically insignificant. Analysis of SMM subgroups revealed increased CVD risk for Bisexual men and decreased CVD risk for both Gay and Homosexually-experienced Heterosexual men when compared to Heterosexual men. Differences in CVD risk persisted for only Bisexual and Homosexually-experienced Heterosexual men after adjustment for education and history of hard drug use. Subgroups of SMM are at increased risk for CVD compared to Heterosexual men, and this increased risk cannot be completely attributed to differences in demographic characteristics or negative health behaviors.
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