Planar-Waveguide Interferometers for Chemical Sensing
Planar-Waveguide Interferometers for Chemical Sensing
复制标题
用于化学传感的平面波导干涉仪
DOI：
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
D. P. Campbell
中科院分区：
文献类型：
--
作者：
D. P. Campbell
干涉测量是一种光学技术，可比较沿相似路径传播的两束光束所经历的差异。平面波导具有对波导表面正上方体积中的折射率变化敏感的渐逝场。在该区域内放置化学敏感薄膜为化学传感奠定了基础。薄膜与分析物的相互作用会改变折射率，导致传播光速或相位沿与折射率变化相反的方向变化。为了测量这种变化，与传感光束相邻的参考传播光束与传感光束进行光学组合，从而产生明暗条纹交替的干涉图案。当传感臂发生化学或物理变化时，干涉图案会发生变化，产生正弦输出。波导和干涉仪有多种设计，但都依赖于倏逝场与化学选择性薄膜相互作用来产生测量响应。传感机制可以是被动的（物理变化）或主动的（薄膜中的反应位点）。通过明智地选择传感薄膜，干涉仪可以设计用于检测各种化学和生物材料。具有多种不同传感薄膜的多干涉仪装置可用于通过特定传感化学或通过分析一系列不同薄膜的图案响应来检测和识别各种不同的化学或生物分析物。
Interferometry is an optical technique that compares the differences experienced by two light beams traveling along similar paths. Planar waveguides have evanescent fields sensitive to changes in the index of refraction in the volume immediately above the waveguide surface. Placing a chemically sensitive film within this region provides the basis for chemical sensing. Film–analyte interactions change the index of refraction, causing the propagating light speed or phase to change in a direction of opposite sign to that of the index change. To measure this change, a reference propagating beam, which is adjacent to the sensing beam, is combined optically with the sensing beam, thus creating an interference pattern of alternating dark and light fringes. When chemical or physical changes occur in the sensing arm, the interference pattern shifts, producing a sinusoidal output. Waveguides and interferometers come in a variety of designs, but all rely on the evanescent field interacting with a chemically selective film to produce a measured response. The sensing mechanism can be passive (a physical change) or active (reactive sites in the film). Through a judicious choice of sensing films, interferometers can be designed to detect a wide variety of chemical and biological materials. Multi-interferometer devices with several different sensing films can be used to detect and identify a variety of different chemical or biological analytes either through specific sensing chemistry or through analysis of patterned response from an array of different films.
卤化碳引起的心脏敏化性心律失常的可能机制。
影响因子：
5
作者：
Jiao,Zhe;DeJesús,VíctorR;Iravanian,Shahriar;Campbell,DanielP;Xu,Jie;Vitali,JuanA;Banach,Kathrin;Fahrenbach,John;DudleyJr,SamuelC
通讯作者：
DudleyJr,SamuelC