Metabolic brain measurements in the newborn: Advances in optical technologies.
Metabolic brain measurements in the newborn: Advances in optical technologies.
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DOI：
10.14814/phy2.14548
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发表时间：
2020-09
影响因子：
2.5
通讯作者：
Tachtsidis I
中科院分区：
文献类型：
--
作者：
Bale G;Mitra S;Tachtsidis I
新生儿重症监护中的新生儿监护正在推动新生儿脑监护的技术界限，以改善患者的预后。迫切需要一种床旁、真实的时间监测来评估脑损伤严重程度和神经发育结局，特别是对于患有缺氧缺血性脑损伤的足月新生儿。这篇专题综述讨论了为什么脑组织代谢监测在这组婴儿中很重要，并介绍了目前在新生儿重症监护室（NICU）中用于代谢监测的神经监测技术。介绍了可以监测床侧大脑代谢变化和大脑血流动力学的新光学技术。这些新兴技术的早期研究已经证明了它们有潜力在真实的时间内提供有关患病新生儿大脑生理变化的连续信息。这些新工具的承诺，以及他们的潜在局限性进行了讨论。可用的代谢神经监测技术的总结如摘要图所示。
Neonatal monitoring in neonatal intensive care is pushing the technological boundaries of newborn brain monitoring in order to improve patient outcome. There is an urgent need of a cot side, real time monitoring for assessment of brain injury severity and neurodevelopmental outcome, in particular for term newborn infants with hypoxic‐ischemic brain injury. This topical review discusses why brain tissue metabolic monitoring is important in this group of infants and introduces the currently used neuromonitoring techniques for metabolic monitoring in the neonatal intensive care unit (NICU). New optical techniques that can monitor changes in brain metabolism together with brain hemodynamics at the cot side are presented. Early studies from these emerging technologies have demonstrated their potential to deliver continuous information regarding cerebral physiological changes in sick newborn infants in real time. The promises of these new tools as well as their potential limitations are discussed. A summary of the available metabolic neuromonitoring techniques is shown in the abstract diagram.