Prevalence of counterfeit anthelminthic medicines: a cross-sectional survey in Cambodia
Prevalence of counterfeit anthelminthic medicines: a cross-sectional survey in Cambodia
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DOI：
10.1111/j.1365-3156.2010.02494.x
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发表时间：
2010-05-01
影响因子：
3.3
通讯作者：
Kimura, Kazuko
中科院分区：
文献类型：
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作者：
Khan, Mohiuddin Hussain;Okumura, Junko;Kimura, Kazuko
目的评估柬埔寨假冒驱虫药的流行情况，并确定影响因素。方法从私人药店收集常用驱虫药。仔细观察药品，包括其注册标签，并与制造商和药品监管机构一起调查药品的真实性。样品在柬埔寨国家保健品质量控制中心进行高效液相色谱分析。结果从137家药店采集了203份驱虫药样品。国内产品占36.9%。经核实注册的196个样品中，未注册样品占15.8%。在成功进行真伪调查的 165 个样品中，有 7 个（4.2%）被鉴定为假货。所有这些药品都是以开放包装或容器形式购买的，其中大多数是外国制造和/或未经注册的。结论我们的调查结果敦促严格执行药品注册，并对未经注册的药品保持警惕，以打击柬埔寨的假药。
P>ObjectivesTo assess the prevalence of counterfeit anthelminthic medicines in Cambodia, and to determine influential factors.MethodsCommonly used anthelminthic medicines were collected from private drug outlets. Medicines were carefully observed including their registration labelling, and their authenticity was investigated with the manufacturers and the Medicines Regulatory Authorities. Samples were analysed by High-Performance Liquid Chromatography at the National Health Product Quality Control Centre, Cambodia.ResultsTwo hundred and three samples of anthelminthics were collected from 137 drug stores. Domestic products constituted 36.9%. Of 196 samples which were verified for registration, 15.8% were not registered. Of 165 samples successfully investigated for their authenticity, 7 (4.2%) were identified as counterfeit. All of these medicines were purchased in open packs or containers, and most of them were foreign manufactured and/or without registration.ConclusionThe results of our survey urge strict implementation of drug registration and vigilance on the availability of unregistered medicines to combat counterfeit medicines in Cambodia.