CORTICAL AND CENTRAL ATROPHY IN CHRONIC-SCHIZOPHRENIA - A CONTROLLED-STUDY
CORTICAL AND CENTRAL ATROPHY IN CHRONIC-SCHIZOPHRENIA - A CONTROLLED-STUDY
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DOI：
10.1111/j.1600-0447.1982.tb00818.x
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发表时间：
1982-01-01
影响因子：
6.7
通讯作者：
MADKOUR, O
中科院分区：
文献类型：
--
作者：
OKASHA, A;MADKOUR, O
本文对43例病程5年以上、年龄60岁以下的慢性精神分裂症患者和39例年龄、性别、文化程度相匹配的正常人进行了脑CT检查。对照组和精神分裂症患者之间在皮质萎缩方面没有统计学差异（通过纵裂和侧裂以及平均脑沟宽度测量）。高度显着差异，发现关于中央萎缩。第三脑室正常者占9.3%，轻度扩大者占37.2%，中度扩大者占48.8%，极度扩大者占4.7%。反映侧脑室扩大的切拉膜指数46.5%有变化，9.3%有轻度变化，44.2%正常。大量慢性精神分裂症患者伴有中枢萎缩。
CT (computed tomography) of the brain was carried out in 43 chronic schizophrenics of more than 5 yr duration and less than 60 yr of age, and 39 normal controls matched for age, sex and education. There was no statistical difference between controls and schizophrenics as regards cortical atrophy (as measured by the interhemispheric and Sylvian fissures and mean sulcal width). Highly significant differences were found regarding central atrophy. Third ventricle measurements were normal in 9.3%, there was slight enlargement in 37.2%, moderate in 48.8% and extreme in 4.7%. The cella media index denoting lateral ventricle dilatation showed changes in 46.5%, slight in 9.3% and the remaining 44.2% were normal. A large number of chronic schizophrenics have an associated central atrophy.