STUDIES OF INACTIVATED INFLUENZA-VIRUS VACCINES IN HOSPITAL EMPLOYEES - REACTOGENICITY AND ABSENTEEISM
STUDIES OF INACTIVATED INFLUENZA-VIRUS VACCINES IN HOSPITAL EMPLOYEES - REACTOGENICITY AND ABSENTEEISM
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DOI：
10.1093/infdis/136.supplement_3.s533
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发表时间：
1977-01-01
影响因子：
6.4
通讯作者：
CASTLE, M
中科院分区：
文献类型：
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作者：
MOSTOW, SR;EICKHOFF, TC;CASTLE, M
在成年志愿者雇员中评估了大规模流感疫苗接种计划对大型医疗中心运营的影响，这些志愿者雇员以双盲方式通过喷射注射枪接种了乙醚裂解或全病毒双价流感疫苗。每个志愿人员填写一份反应信息表，护士监测体温，并收集护理处和房舍管理处雇员缺勤情况的数据。这项研究的结果表明，群众运动并没有对缺勤产生不利影响。然而，全病毒疫苗引起的局部、全身和发热反应明显多于裂解病毒疫苗。纯化的灭活流感病毒疫苗可以在大规模活动中向医院工作人员接种，而不会对医院的运营产生不利影响。
The impact of a mass influenza vaccination program on the operation of a major medical center was evaluated in adult volunteer employees who were given either ether-split or whole-virus bivalent influenza vaccine in a double-blind manner by jet-injector gun. Each volunteer completed a reaction information form, nurses monitored temperatures, and data on absenteeism of the employees of the Nursing Service and the Building Management Service were collected. The results of this study demonstrated that the mass campaign did not adversely affect absenteeism. However, the whole-virus vaccine caused significantly more local, systemic, and febrile reactions than the split-virus vaccine. Purified inactivated influenza virus vaccines can be given in a mass campaign to hospital personnel without adversely affecting the operation of the hospital.