Antioxidant and immune defences of rainbow trout (Oncorhynchus mykiss) offered plant oils differing in fatty acid profiles from early stages
Antioxidant and immune defences of rainbow trout (Oncorhynchus mykiss) offered plant oils differing in fatty acid profiles from early stages
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DOI：
10.1111/j.1365-2095.2009.00715.x
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发表时间：
2011-04
影响因子：
3.5
通讯作者：
V. Kiron;J. Thawonsuwan;A. Panigrahi;J. Scharsack;S. Satoh
中科院分区：
文献类型：
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作者：
V. Kiron;J. Thawonsuwan;A. Panigrahi;J. Scharsack;S. Satoh
抗氧化防御和免疫反应的虹鳟鱼（虹鳟鱼mykiss），已收到植物油，丰富的n-3多不饱和脂肪酸（PUFA;亚麻籽油）或n-6 PUFA（红花油）抗原暴露后进行了评估。在这项研究中使用的鱼已经提供了18个月的饮食从第一次喂养。将各组虹鳟鱼腹腔注射福尔马林灭活的细菌（嗜水气单胞菌）或假注射，24 h后进行观察。虽然鱼喂红花油似乎是在相对较大的氧化应激，抗氧化防御（超氧化物歧化酶，过氧化氢酶，谷胱甘肽过氧化物酶）是有效的，在那些喂亚麻籽油。体液（交替补体活性和溶菌酶活性）和细胞（吞噬细胞活性和淋巴细胞增殖）免疫反应没有显着影响所提供的油。除了活性氧的产生是显着更大的亚麻籽油喂养的鱼，这两个群体并没有显着不同的抗原暴露后，他们的免疫反应。因此，鱼喂养的红花油是缺乏n-3多不饱和脂肪酸是能够维持大部分的关键反应类似于那些喂养亚麻籽油，这表明植物油的两种脂肪酸类别是有效的，这淡水鱼。
The antioxidant defence and immune response of rainbow trout (Oncorhynchus mykiss) that had received plant oils, rich in either n-3 polyunsaturated fatty acids (PUFA; linseed oil) or n-6 PUFA (safflower oil) was evaluated upon antigen exposure. The fish employed in this study had been offered the diets for 18 months from the first feeding. Rainbow trout from each group were injected intraperitoneally with formalin-killed bacteria (Aeromonas hydrophila) or were sham-injected and observations were made 24 h later. Though the fish fed safflower oil seemed to be under relatively greater oxidative stress, the antioxidant defences (superoxide dismutase, catalase, glutathione peroxidase) were as effective as in those fed linseed oil. The humoral (alternate complement activity and lysozyme activity) and cellular (phagocytic activity and lymphocyte proliferation) immune responses were not significantly affected by the oil offered. With the exception of reactive oxygen production that was significantly greater in the linseed oil fed fish, both groups did not differ greatly in their immune responses after antigen exposure. Thus, fish fed safflower oil that was deficient in n-3 PUFA was able to sustain most of the critical responses similar to those fed linseed oil suggesting that plant oils of both fatty acid categories were effective for this fresh water fish.