Validation of clinic weights from electronic health records against standardized weight measurements in weight loss trials.
Validation of clinic weights from electronic health records against standardized weight measurements in weight loss trials.
复制标题
在减肥试验中，从电子健康记录中对标准化重量测量的临床重量验证。
DOI：
10.1002/oby.21737
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发表时间：
2017-02
期刊：
影响因子：
--
通讯作者：
Ma J
中科院分区：
文献类型：
--
作者：
Xiao L;Lv N;Rosas LG;Au D;Ma J
To validate clinic weights in electronic health records against researcher-measured weights for outcome assessment in weight loss trials. Clinic and researcher-measured weights from a published trial (“BE WELL”) were compared using Lin’s concordance correlation coefficient (CCC), Bland and Altman’s limits-of-agreement, and polynomial regression model. Changes of clinic and researcher-measured weights in BE WELL and another trial, “E-LITE,” were analyzed using growth curve modeling. Among BE WELL (n=330) and E-LITE (n=241) participants, 96% and 90% had clinic weights (mean (SD) of 5.8 (6.1) and 3.7 (3.9) records) over 12 and 15 months of follow-up, respectively. The CCC was 0.99 and limits-of-agreement plots showed no pattern between or within treatment groups, suggesting overall good agreement between researcher-measured and nearest-in-time clinic weights up to3 months. The 95% confidence intervals for predicted percent differences fell within +/−3% for clinic weights within 3 months of the researcher-measured weights. Furthermore, the growth curve slopes for clinic and researcher-measured weights by treatment group didn’t differ significantly, suggesting similar inferences about treatment effects over time, in both trials. Compared with researcher-measured weights, close-in-time clinic weights showed high agreement and inference validity. Clinic weights can be a valid pragmatic outcome measure in weight loss studies.
