Network meta-analysis for indirect treatment comparisons

Network meta-analysis for indirect treatment comparisons
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DOI:
10.1002/sim.1201
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发表时间:
2002-08-30
影响因子:
2
通讯作者:
Lumley, T
Lumley, T
中科院分区:
医学3区
文献类型:
--
作者:
Lumley, T

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我提出的方法来评估两种治疗方法的相对有效性时,他们没有直接比较在一个随机试验中,但每一个比较其他治疗。这些网络荟萃分析技术允许估计任何给定治疗效果的异质性和来自不同治疗对的证据的不一致性("不一致性")。一个简单的估计程序,使用线性混合模型,并用于急性心肌梗死治疗的荟萃分析。版权所有(C)2002约翰威利父子有限公司
I present methods for assessing the relative effectiveness of two treatments when they have not been compared directly in a randomized trial but have each been compared to other treatments. These network meta-analysis techniques allow estimation of both heterogeneity in the effect of any given treatment and inconsistency ('incoherence') in the evidence from different pairs of treatments. A simple estimation procedure using linear mixed models is given and used in a meta-analysis of treatments for acute myocardial infarction. Copyright (C) 2002 John Wiley Sons, Ltd.