Systemic candidiasis in a dog, developing spondylitis
Systemic candidiasis in a dog, developing spondylitis
复制标题
DOI：
10.1292/jvms.68.1117
复制
发表时间：
2006-10-01
影响因子：
1.2
通讯作者：
Kotani, Takao
中科院分区：
文献类型：
--
作者：
Kuwamura, Mitsuru;Ide, Mika;Kotani, Takao
一只4岁的雄性柴犬最初表现为不明原因的疼痛和对触摸的超敏反应。7天后，该犬出现共济失调、后腿无力和关节弯曲。该犬在发病后20天死亡。验尸报告显示在胸椎体内有一肿块。组织学上，肿块由肉芽肿性炎症组成，包括真菌微生物，其化学上为白色念珠菌阳性。在全身淋巴结、肾脏、胰腺、脾脏、前列腺、甲状腺和心脏中观察到类似的肉芽肿性病变。该病例被诊断为系统性念珠菌病伴脊柱炎。
A 4-year-old male Shiba dog initially presented with pain of an undetermined origin and hypersensitivity to touch. Seven days later, the dog developed ataxia, hind-leg weakness and knuckling. The dog died on 20 days after presentation. Postmortem examination revealed a mass in the body of thoracic vertebra. Histopathologically, the mass consisted of granulomatous inflammation, including fungal organisms that were immunohistochemically positive for Candida albicans. Similar granulomatous lesions were observed in the systemic lymph nodes, kidneys, pancreas, spleen, prostate gland, thyroid glands and heart. This case was diagnosed as systemic candidiasis with spondylitis.