Detailed mapping of prostate carcinoma foci

Detailed mapping of prostate carcinoma foci
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前列腺癌病灶的详细绘图

DOI：
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发表时间：
2000
期刊：
Cancer
影响因子：
6.2
通讯作者：
P. Troncoso
P. Troncoso
中科院分区：
医学1区
文献类型：
--
作者：
Michael E. Chen;D. Johnston;Kuang S. Tang;R. Babaian;P. Troncoso

文献摘要

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前列腺癌具有相当大的解剖异质性。前列腺癌分布的详细特征可能会改进检测程序和活检策略。我们绘制了180个连续切片的全子宫颈癌根治术标本的所有607个肿瘤病灶，并使用计算机算法绘制和总结了这些病灶的分布。我们研究了标本和临床变量是否预测肿瘤分布的差异。
Prostate carcinoma exhibits considerable anatomic heterogeneity. Detailed characterization of prostate carcinoma distribution could lead to improved detection procedures and biopsy strategies. We mapped all 607 tumor foci from 180 serially sectioned whole mount radical prostatectomy specimens and used a computer algorithm to plot and summarize the distribution of these foci. We investigated whether specimen and clinical variables predicted differences in tumor distribution.