DIAGNOSTIC VALUE OF AN IMMUNOASSAY TO DETECT ANTI CAMPYLOBACTER PYLORI ANTIBODIES IN NON-ULCER DYSPEPSIA

DIAGNOSTIC VALUE OF AN IMMUNOASSAY TO DETECT ANTI CAMPYLOBACTER PYLORI ANTIBODIES IN NON-ULCER DYSPEPSIA
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免疫测定检测抗幽门弯曲菌抗体对非溃疡性消化不良的诊断价值

DOI:
10.1016/s0140-6736(89)92761-x
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发表时间:
1989
期刊:
The Lancet
影响因子:
--
通讯作者:
J. Arends
J. Arends
中科院分区:
--
文献类型:
--
作者:
R. Loffeld;J. Flendrig;E. Stobberingh;J. V. van Spreeuwel;J. Arends

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应用酶联免疫吸附试验(ELISA)检测70例非溃疡性消化不良患者血清中抗幽门弯曲菌IgG抗体。48例幽门螺杆菌相关性胃炎患者的ELISA平均光密度(OD)明显高于22例正常胃窦粘膜和无幽门螺杆菌的患者。弯曲杆菌相关性胃炎的阳性和阴性预测值分别为100%高于OD 2.10和低于OD 1.00。血清学检查可取代内镜检查诊断弯曲杆菌相关性胃炎。
An enzyme-linked immunosorbent assay (ELISA) for detection of IgG antibodies againstCampylobacter pyloriwas used to examine sera from 70 patients with non-ulcer dyspepsia. 48 patients had Cpyloriassociated gastritis according to culture or histology; mean optical density (OD) of the ELISA was significantly higher than that for the 22 patients with normal antral mucosa and absence ofC pylori. Positive and negative predictive values for campylobacter-associated gastritis were 100% above OD 2·10 and below OD 1·00, respectively. Serology might replace endoscopy in the diagnosis of campylobacter-associated gastritis.
幽门弯曲杆菌感染的流行病学:种族考虑。
DOI: --
发表时间: 1988
期刊: Scandinavian journal of gastroenterology. Supplement
影响因子: --
作者:
Graham,DY;Klein,PD;Opekun,AR;Boutton,TW;EvansJr,DJ;Evans,DG;Alpert,LC;Michaletz,PA;Yoshimura,HH;Adam,E
通讯作者: Adam,E