Changes in childhood vaccination coverage over time in the Democratic Republic of the Congo
Changes in childhood vaccination coverage over time in the Democratic Republic of the Congo
复制标题
DOI：
10.1371/journal.pone.0217426
复制
发表时间：
2019-05-24
期刊：
影响因子：
3.7
通讯作者：
Rimoin, Anne W.
中科院分区：
文献类型：
--
作者：
Alfonso, Vivian H.;Bratcher, Anna;Rimoin, Anne W.
尽管疫苗接种率有所提高，但与疫苗可预防疾病相关的负担、发病率和死亡率仍然很高。在刚果民主共和国 (DRC)，可能不可靠的数据和地区不同的计划规定要求更好地了解疫苗接种覆盖率及其在国家和省一级随时间的变化。为了评估刚果民主共和国完全接种疫苗的儿童比例随时间的变化，从 2007 年和 2013-2014 年人口与健康调查 (DHS) 中获取了 12-59 个月大儿童的疫苗接种史。对国家和省级的变化进行了评估，以确定潜在的地理差异。国土安全部各次疫苗接种覆盖率提高了 70%：2007 年和 2013-2014 年 12-59 个月大的儿童达到全面疫苗接种标准的比例分别为 26%（n(2007) = 3032 和 n(2013-14) = 6619）。同样，两次国土安全部的总体趋势是，随着出生年份的增加，疫苗接种覆盖率也随之增加。免疫变化存在地域差异，在第二个时间点，大多数中部和东部省份的疫苗接种覆盖率有所增加，而大多数北部、西部和南部省份的疫苗接种覆盖率有所下降。使用具有全国代表性的数据，我们发现了疫苗接种覆盖率随时间的显着变化，这可能有助于为未来的政策、干预措施和研究提供信息，以提高刚果民主共和国儿童的疫苗接种率。这项研究是针对刚果民主共和国人口的首次此类研究，为更好地了解疫苗接种覆盖率随时间变化的趋势迈出了重要的第一步。
Despite increased vaccination rates, the burden, morbidity and mortality associated with vaccine preventable diseases remains high. In the Democratic Republic of the Congo (DRC), potentially unreliable data and geographically varied program provision call for a better understanding of vaccination coverage and its changes over time at the country and province level. To assess changes in the proportion of children who were fully vaccinated over time in the DRC, vaccination histories for children 12-59 months of age were obtained from both the 2007 and 2013-2014 Demographic and Health Surveys (DHS). Changes were assessed, both at the country-and province-levels, to identify potential geographic variations. Vaccination coverage improved 70% between the DHS waves: 26% compared to 44% of 12-59 month-old children met full vaccination criteria in 2007 and 2013-2014, respectively (n(2007) = 3032 and n(2013-14) = 6619). Similarly, there was an overall trend across both DHS waves where as year of birth increased, so did vaccination coverage. There was geographic variation in immunization changes with most central and eastern provinces increasing in coverage and most northern, western and southern provinces having decreased vaccination coverage at the second time point. Using nationally representative data, we identified significant changes over time in vaccination coverage which may help to inform future policy, interventions and research to improve vaccination rates among children in the DRC. This study is the first of its kind for the population of DRC and provides an important initial step towards better understanding trends in vaccination coverage over time.