CT IN THE DIFFERENTIAL-DIAGNOSIS BETWEEN ALZHEIMERS-DISEASE AND VASCULAR DEMENTIA
CT IN THE DIFFERENTIAL-DIAGNOSIS BETWEEN ALZHEIMERS-DISEASE AND VASCULAR DEMENTIA
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DOI：
10.1111/j.1600-0404.1987.tb07931.x
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发表时间：
1987-04-01
影响因子：
3.5
通讯作者：
PALO, J
中科院分区：
文献类型：
--
作者：
ERKINJUNTTI, T;KETONEN, L;PALO, J
对连续入院的阿尔茨海默病（AD）（n = 68）、多发梗塞性痴呆（MID）（n = 79）和可能的血管性痴呆（PVD）（n = 46）患者进行前瞻性头颅CT研究。MID组88.6%和PVD组41.3%的患者在CT上至少有一个脑梗死，但只有1例患者（1.5%）患有AD。白色物质低衰减（WMLA）也可将MID和PVD与AD区分开来，尤其是在75岁或更小的患者以及轻度或中度痴呆患者中。在所有类型中，CT显示的脑萎缩与痴呆程度呈正相关。CT上的脑萎缩和WMLA，而不是脑萎缩，似乎是血管性痴呆和退行性痴呆之间的鉴别诊断价值。
A prospective series of consecutively admitted patients with Alzheimer''s disease (AD) (n = 68), multi-infarct dementia (MID) (n = 79) and probable vascular dementia (PVD) (n = 46) were studied by CT of the head. In MID 88.6% and in PVD 41.3% of the patients had at least one brain infarct on CT, but only one patient (1.5%) with AD. White matter low attenuation (WMLA) also differentiated MID and PVD from AD, especially among patients aged 75 years or less, and with mild or moderate dementia. In all types, brain atrophy on CT had a positive correlation with the degree of dementia. Infarcts and WMLA on CT, but not brain atrophy seem to be of differential diagnostic value between vascular and degenerative dementia.