Sinus floor augmentation using large (1-2 mm) or small (0.25-1 mm) bovine bone mineral particles: a prospective, intra-individual controlled clinical, micro-computerized tomography and histomorphometric study
Sinus floor augmentation using large (1-2 mm) or small (0.25-1 mm) bovine bone mineral particles: a prospective, intra-individual controlled clinical, micro-computerized tomography and histomorphometric study
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DOI：
10.1111/j.1600-0501.2010.02032.x
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发表时间：
2011-05-01
影响因子：
4.3
通讯作者：
Shapira, Lior
中科院分区：
文献类型：
--
作者：
Chackartchi, Tali;Iezzi, Giovana;Shapira, Lior
ObjectivesTo比较两种不同粒度的牛骨矿物质（BBM）在上颌窦底提升术后的新骨形成量，并应用临床、CT和组织学技术进行比较。6至9个月后，骨样本被检索和analysed.ResultsResults：两组是没有不同的垂直骨高度后实现增强，术后并发症和最大扭矩插入种植体。Micro-CT测量无法检测到组间骨体积的统计学显著差异（小颗粒组有新骨更多的趋势）。组织形态学分析显示，两种颗粒尺寸产生相同的骨形成模式，围绕移植物颗粒，并产生网络形状，在BBM颗粒之间“桥接”。在两组中，直接在BBM颗粒表面观察到多核巨细胞，可能是破骨细胞。结论两种大小的BBM颗粒在临床上和组织学上均能达到窦底提升术的目的。引用本文：Chackartchi T，Iezzi G，Goldstein M，Klinger A，Soskolne A，Piattelli A，Shapira L.使用大（1-2 mm）或小（0.25-1 mm）牛骨矿物质颗粒进行窦底填充：一项前瞻性、个体内对照临床、微型计算机断层扫描和组织形态学研究。Res 22，2011; 473-480doi：10.1111/j.1600-0501.2010.02032.x.
ObjectivesTo compare the amount of newly formed bone after sinus floor augmentation with two different particle sizes of bovine bone mineral (BBM) using clinical, micro-computerized tomography (CT) and histological techniques.MethodsBilateral sinus floor augmentations were performed in 10 patients. Six to 9 months later, bone samples were retrieved and analyzed.ResultsResults: Both groups were not different in vertical bone height achieved after augmentation, post-operative complications and maximal torque for the insertion of implants. Micro-CT measurements could not detect a statistically significant difference in bone volume between the groups (with a tendency for new more bone in the small granules group). Histomorphometric analysis revealed that both granule sizes produced the same pattern of bone formation, surrounding the graft granules, and producing a shape of a network, "bridging" between the BBM particles. Multi-nucleated giant cells, probably osteoclasts, were observed directly on the BBM particle surface in both groups. The osteoclast-like cells preferred the small-size BBM particles and not the large particles both in the small-size and the large-size granules group.ConclusionBoth sizes of BBM granules preformed equally and achieved the aim of the sinus floor augmentation procedure clinically and histologically.To cite this article:Chackartchi T, Iezzi G, Goldstein M, Klinger A, Soskolne A, Piattelli A, Shapira L. Sinus floor augmentation using large (1-2 mm) or small (0.25-1 mm) bovine bone mineral particles: a prospective, intra-individual controlled clinical, micro-computerized tomography and histomorphometric study.Clin. Oral Impl. Res 22, 2011; 473-480doi: 10.1111/j.1600-0501.2010.02032.x.