CURING OF A PLASMID IS CORRELATED WITH AN ATTENUATION OF VIRULENCE IN THE MARINE FISH PATHOGEN VIBRIO-ANGUILLARUM
CURING OF A PLASMID IS CORRELATED WITH AN ATTENUATION OF VIRULENCE IN THE MARINE FISH PATHOGEN VIBRIO-ANGUILLARUM
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DOI：
10.1128/iai.27.3.897-902.1980
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发表时间：
1980-01-01
影响因子：
3.1
通讯作者：
SCHIEWE, MH
中科院分区：
文献类型：
--
作者：
CROSA, JH;HODGES, LL;SCHIEWE, MH
将含有氨苄青霉素抗性决定子的转座子A序列tn1从RP 4转座到海鱼病原体鳗弧菌的质粒中。通过分析氨苄青霉素抗性表型的分离来确定质粒损失的治愈实验显示了毒力与特定的鳗弧菌质粒类别的关联。
The transposon A sequence tn1 containing the ampicillin resistance determinants was transposed from RP4 to a plasmid of the marine fish pathogen V. anguillarum. Curing experiments in which plasmid loss was determined by analysis of the segregation of the ampicillin resistance phenotype showed the association of virulence with the specific V. anguillarum plasmid class.