Quality of life after stroke: a prospective longitudinal study
Quality of life after stroke: a prospective longitudinal study
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DOI：
10.1007/s11136-010-9810-6
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发表时间：
2011-08-01
影响因子：
3.5
通讯作者：
Howard, George
中科院分区：
文献类型：
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作者：
Haley, William E.;Roth, David L.;Howard, George
为了测量中风对生活质量（QOL）的影响，并分析种族、性别、年龄、收入或独居是否会调节这些变化，采用前瞻性纵向方法。卒中地理和种族差异原因研究中无卒中史的参与者完成基线SF-12心理（MCS）和身体成分总结（PCS）测量和抑郁量表。在医学记录的中风事件发生后，136名参与者和136名人口统计学匹配的无中风对照组重复测量（M = 1231天后）。卒中参与者在所有三项生活质量测量中都比对照组明显恶化。PCS的控制也显著下降。在调整协变量后，卒中与对照组受试者的标准化效应量在三个测量中相似，范围从。366到。465个标准差单位。独居的中风幸存者抑郁症状增加的风险更大。中风后生活质量会多次下降，而社会孤立会增加中风后抑郁的风险。我们的前瞻性设计和使用基于人群的样本与匹配的对照表明，在身体健康和精神健康的生活质量领域有相似的影响，并在理解中风对生活质量的影响方面提供了独特的优势。
To measure the impact of stroke on quality of life (QOL), and analyze whether race, gender, age, income, or living alone moderated those changes, using prospective longitudinal methods.Participants in the REasons for Geographic and Racial Differences in Stroke study without history of stroke completed baseline SF-12 Mental (MCS) and Physical Component Summary (PCS) measures and a depression scale. Measures were repeated (M = 1231 days later) by 136 participants after an incident medically documented stroke and by 136 demographically matched stroke-free controls.Stroke participants showed significant worsening than controls in all three QOL measures. Controls also declined significantly in PCS. Standardized effect sizes for stroke versus control participants after adjusting for covariates were similar across the three measures and ranged from .366 to .465 standard deviation units. Stroke survivors who lived alone were at greater risk for increases in depressive symptoms.Multiple declines in QOL occur after stroke, and social isolation heightens risk for increasing depression after stroke. Our prospective design and use of a population-based sample with matched controls suggests similar effects in both physical health and mental health QOL domains and offers unique strengths in understanding the impact of stroke on QOL.