Structure and organization of paramyxovirus particles.
Structure and organization of paramyxovirus particles.
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DOI:
10.1016/j.coviro.2017.05.004
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发表时间:
2017-06
影响因子:
5.9
通讯作者:
Plemper RK
中科院分区:
文献类型:
--
作者:
Cox RM;Plemper RK
The paramyxovirus family comprises major human and animal pathogens such as measles virus (MeV), mumps virus (MuV), the parainfluenzaviruses, Newcastle disease virus (NDV), and the highly pathogenic zoonotic hendra (HeV) and nipah (NiV) viruses. Paramyxovirus particles are pleomorphic, with a lipid envelope, nonsegmented RNA genomes of negative polarity, and densely packed glycoproteins on the virion surface. A number of crystal structures of different paramyxovirus proteins and protein fragments were solved, but the available information concerning overall virion organization remains limited. However, recent studies have reported cryo-electron tomography-based reconstructions of Sendai virus (SeV), MeV, NDV, and human parainfluenza virus type 3 (HPIV3) particles and a surface assessment of NiV-derived virus-like particles (VLPs), which have yielded innovative hypotheses concerning paramyxovirus particle assembly, budding, and organization. Following a summary of the current insight into paramyxovirus virion morphology, this review will focus on discussing the implications of these particle reconstructions on the present models of paramyxovirus assembly and infection.
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DOI:
10.1016/j.micron.2005.10.001
发表时间:
2006
期刊:
Micron (Oxford, England : 1993)
影响因子:
--
作者:
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通讯作者:
Dowsett B
影响因子:
5.4
作者:
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通讯作者:
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影响因子:
5.4
作者:
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影响因子:
5.6
作者:
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通讯作者:
Yeo, RP
DOI:
10.1073/pnas.1210275109
发表时间:
2012-08-28
影响因子:
11.1
作者:
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通讯作者:
Rossmann, Michael G.