Early gamma response in human neuroelectric activity is correlated with neuropsychological test scores
Early gamma response in human neuroelectric activity is correlated with neuropsychological test scores
复制标题
DOI：
10.1016/s0304-3940(03)00073-9
复制
发表时间：
2003-04-03
影响因子：
2.5
通讯作者：
Erzengin, ÖU
中科院分区：
文献类型：
--
作者：
Karakas, S;Bekçi, B;Erzengin, ÖU
本研究的目的是调查是否早期，时间锁定的“感觉”伽马波段反应与一组分数来自神经心理学测试。在主动听觉oddball范式下获得神经电反应。在67名健康成年人中，35名显示出时间锁定的早期伽马，G（+），24名没有，G（-）。在52项神经心理学测验中，G（+）组和G（-）组在威斯康星州卡片分类测验、韦氏记忆量表修订版和连续数字学习测验的基础上存在差异。Logistic回归分析结果具有统计学意义（预测成功率93.33%）。结果表明，早期伽马反应可以根据神经心理学测试表现进行分类，因此与更高的认知功能相关，支持大脑自下而上与自上而下处理相结合的观点。(C)2003爱思唯尔科学爱尔兰有限公司保留所有权利。
The goal of this study was to investigate whether early, time-locked 'sensory' gamma band response is correlated with a set of scores derived from neuropsychological tests. Neuroelectric responses were obtained under active auditory oddball paradigm. Of 67 reportedly healthy adults, 35 displayed time-locked early gamma, G (+), and 24 did not, G (-). Out of 52 neuropsychological test scores, G (+) and G (-) groups differed on the basis of Wisconsin Card Sorting Test, Wechsler Memory Scale-Revised and Serial Digit Learning Test scores. Results of logistic regression analysis was statistically reliable (overall success rate of prediction: 93.33%). The results showed that early gamma response can be classified on the basis of neuropsychological test performance and is thus associated with higher cognitive functions, supporting the view that brain integrates bottom-up with top-down processing. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.