Pathogenicity of the Aedes albopictus Parvovirus (AaPV), a denso-like virus, for Aedes aegypti mosquitoes
Pathogenicity of the Aedes albopictus Parvovirus (AaPV), a denso-like virus, for Aedes aegypti mosquitoes
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DOI：
10.1006/jipa.1996.0100
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发表时间：
1996-11-01
影响因子：
3.4
通讯作者：
Bergoin, M
中科院分区：
文献类型：
--
作者：
Barreau, C;Jousset, FX;Bergoin, M
AaPV是从白纹伊蚊C6/36细胞系中分离到的一种致密型病毒，经口感染埃及伊蚊1~3龄幼虫后，其致病性极强，1龄幼虫10天内死亡率达90%。温度、幼虫密度、虫态、与感染性颗粒接触时间等因素对感染均有影响。感染三龄幼虫后存活的雌虫体内病毒滴度达10（8）TCID50。成蚊对病毒接种和病毒DNA的细胞转染敏感。组织学和超微结构研究表明，除中肠外，几乎所有幼虫组织中都存在致密的细胞核。(C)出版社：Academic Press，Inc.
AaPV, a dense-like virus isolated from a C6/36 clone of the Aedes albopictus cell line, proved to be very pathogenic for Aedes aegypti first and third instar larvae following per os infection, The mortality reached 90% in 10 days for larvae infected at the first instar. Several factors, such as temperature, larval density and stage, and duration of contact with infectious particles, influenced infection, The virus titer in females surviving infection at the third larval instar reached 10(8) TCID50. Adult mosquitoes were sensitive to virus inoculation and to cytotransfection by viral DNA, Histological and ultrastructural studies revealed the presence of dense nuclei in almost all of the larval tissues with the exception of the midgut. (C) 1996 Academic Press, Inc.