The Oxford Handbook of the Auditory Brainstem
The Oxford Handbook of the Auditory Brainstem
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牛津听觉脑干手册
DOI：
10.1093/oxfordhb/9780190849061.013.21
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Rees A
中科院分区：
文献类型：
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作者：
Rees A
连接大脑两侧的连合纤维位于听觉通路的几个沿着点，这表明它们对声音分析的重要性。本章概述了目前已知的下丘连合（CoIC）的解剖学，生理学和行为的影响-最突出的脑干听觉连合，它与听觉中脑的主要核团，下丘（IC）相互连接。对CoIC的主要贡献来自从一个下丘投射到另一个下丘的神经元，背侧皮质和中央核提供了最广泛的连接。此外，许多上升和下降的听觉中心通过CoIC向IC发送投射，以及位于经典定义的听觉通路之外的各种来源。两个IC之间的互连程度表明它们作为一个单一实体运行。最近在体内的证据表明，CoIC预测调制的声音的频率，水平和位置在IC的神经代表，从而表明在听觉处理的CoIC的重要作用。然而，CoIC对听觉行为影响的证据有限。这一点，加上通过CoIC投射的来源的多样性，表明未知的作用，值得进一步探索。
Commissural fibres interconnecting the two sides of the brain are found at several points along the auditory pathway, thus suggesting their fundamental importance for the analysis of sound. This chapter presents an overview of what is currently known about the anatomy, physiology, and behavioral influences of the commissure of the inferior colliculus (CoIC)—the most prominent brainstem auditory commissure—that reciprocally interconnects the principal nuclei of the auditory midbrain, the inferior colliculi (IC). The primary contribution to the CoIC originates from neurons projecting from one inferior colliculus to the other, with the dorsal cortex and central nucleus providing the most extensive connections. In addition, many ascending and descending auditory centers send projections to the IC via the CoIC, together with diverse sources located outside the classically defined auditory pathway. The degree of interconnection between the two ICs suggests they function as a single entity. Recent in vivo evidence has established that CoIC projections modulate the neural representation of sound frequency, level, and location in the IC, thus indicating an important role for the CoIC in auditory processing. However, there is limited evidence for the influence of the CoIC on auditory behavior. This, together with the diversity of sources projecting via the CoIC, suggest unknown roles that warrant further exploration.