Effects of Smoking Reduction and Cessation on Birth Outcomes in a Scheduled Gradual Reduction Cessation Trial.
Effects of Smoking Reduction and Cessation on Birth Outcomes in a Scheduled Gradual Reduction Cessation Trial.
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DOI：
10.1007/s10995-022-03386-6
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发表时间：
2022-05
影响因子：
2.3
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中科院分区：
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怀孕期间吸烟会影响婴儿出生体重。我们测试了促进计划逐步减少的干预措施是否改善了吸烟孕妇的生育结局。我们还检查了出生结果中的种族差异。我们进行了一项双臂随机对照试验，吸烟的孕妇在怀孕期间接受短信递送的预定逐步减少吸烟(SGR)计划加上支持短信或支持短信。这篇论文的结果是出生结果，包括出生体重和胎龄，从图表审查获得。采用SAS软件中的卡方检验和t检验进行分析。我们接触了2201名有吸烟史的孕妇。在这项研究中招募的314名女性中，290人完成了医疗出院表格(92%)。我们没有发现手臂或种族在出生结果上有任何显著差异。大多数参与者减少了80%的吸烟。每天减少基线香烟50%以上的女性与没有减少基线香烟的女性相比，出生体重增加了335克(p=0.05)。产前检查记录中出现酒精/药物使用与低出生体重相关(p=0.05)。计划中的逐渐减少干预措施并没有改善出生结果。需要进行更多的研究，以帮助改善吸烟和非法药物使用的孕妇的生育结果。
Smoking during pregnancy can affect infant birthweight. We tested whether an intervention that promoted scheduled gradual reduction improved birth outcomes among pregnant women who smoked. We also examined race differences in birth outcomes. We conducted a 2-arm randomized controlled trial where pregnant women who smoked received either SMS text-delivered scheduled gradual smoking reduction (SGR) program plus support texts or support messages only throughout their pregnancy. The outcomes for this paper were birth outcomes including birth weight and gestational age obtained from chart review. Analyses were conducted using chi-square and t-tests in SAS. We approached 2201 pregnant women with smoking history. Of the 314 women recruited into the study, 290 completed a medical release form (92%). We did not find any significant differences in birth outcomes by arm or race. The majority of participants reduced smoking by the 80%. Women who reduced more than 50% of their baseline cigarettes per day had a birth weight increase of 335 g compared to those that did not (p = 0.05). The presence of alcohol/drug use in prenatal visit notes was associated with low infant birth weight (p = 0.05). The scheduled gradual reduction intervention did not improve birth outcomes. Additional research is needed to help improve birth outcomes for pregnant women who engage in tobacco and illicit substance use.