The effects on human sleep and circadian rhythms of 17 days of continuous bedrest in the absence of daylight.
The effects on human sleep and circadian rhythms of 17 days of continuous bedrest in the absence of daylight.
复制标题
在没有日光的情况下连续卧床休息 17 天对人类睡眠和昼夜节律的影响。
作者：
Monk,TH;Buysse,DJ;Billy,BD;Kennedy,KS;Kupfer,DJ
作为涉及各种生命科学实验的更大卧床研究的一部分，在8名健康中年男性中进行了一项关于连续卧床17天并消除日光对昼夜直肠温度节律、情绪、警觉性和睡眠（客观和日记）的影响的研究。睡眠时间为2300至0700小时。比较了三个72小时测量区组：卧床前非卧床休息、早期卧床休息（第5-7天）和晚期卧床休息（第15-17天）。温度节律表现出减少幅度和后期阶段导致卧床休息条件。这与较长的夜间睡眠开始时间和较差的主观评定的睡眠有关，但与任何其他睡眠参数没有可靠的变化有关。姿势和/或日光暴露的日常变化似乎是适当的昼夜节律系统的重要决定因素。
As part of a larger bedrest study involving various life science experiments, a study was conducted on the effects of 17 days of continuous bedrest and elimination of daylight on circadian rectal temperature rhythms, mood, alertness, and sleep (objective and diary) in eight healthy middle-aged men. Sleep was timed from 2300 to 0700 hours throughout. Three 72-hour measurement blocks were compared: ambulatory prebedrest, early bedrest (days 5–7), and late bedrest (days 15–17). Temperature rhythms showed reduced amplitude and later phases resulting from the bedrest conditions. This was associated with longer nocturnal sleep onset latencies and poorer subjectively rated sleep but with no reliable changes in any of the other sleep parameters. Daily changes in posture and/or exposure to daylight appear to be important determinants of a properly entrained circadian system.