MR imaging findings for differentiating cutaneous malignant melanoma from squamous cell carcinoma
MR imaging findings for differentiating cutaneous malignant melanoma from squamous cell carcinoma
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DOI：
10.1016/j.ejrad.2020.109212
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发表时间：
2020-11-01
影响因子：
3.3
通讯作者：
Matsuo, Masayuki
中科院分区：
文献类型：
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作者：
Kawaguchi, Masaya;Kato, Hiroki;Matsuo, Masayuki
目的：本研究旨在评估磁共振成像结果在鉴别皮肤恶性黑色素瘤（cMM）和皮肤鳞状细胞癌（cSCC）中的作用。方法：回顾性分析经组织病理学证实的原发性cMM和原发性cSCC患者的术前MR图像，并对两种病理进行比较。结果：本研究共纳入16例原发性cMM患者（7男9女，年龄45-97岁，中位年龄75岁）和49例原发性cSCC患者（37男12女，年龄46-90岁，中位年龄76岁）。与真皮相比，瘤内T1高强度在cMM中比在cSCC中更常见（50%比4%；p < 0.01）。浅表凹陷（51% vs. 19%, p < 0.05）、浅表不规则缘（55% vs. 25%, p < 0.05）、网状或线状T2高信号（27% vs. 0%, p < 0.05）在cSCC中比在cMM中更常见。结论：cMM主要表现为瘤内T1高信号，而cSCC主要表现为浅表凹陷、浅表不规则边缘、网状或线状T2高信号。
Purpose: This study aimed to assess the efficacy of using MR imaging findings for differentiating cutaneous malignant melanoma (cMM) from cutaneous squamous cell carcinoma (cSCC).Methods: Preoperative MR images of patients with histopathologically proven primary cMM and primary cSCC were retrospectively reviewed and compared between the two pathologies.Results: A total of 16 patients with primary cMM (7 men and 9 women; age range, 45-97 years; median age, 75 years) and 49 with primary cSCC (37 men and 12 women; age range, 46-90 years; median age, 76 years) were enrolled in this study. Intratumoral T1 hyperintensity compared to that of the dermis was more frequently observed in cMM than in cSCC (50 % vs. 4 %; p < 0.01). Superficial depression (51 % vs. 19 %; p < 0.05), superficial irregular margins (55 % vs. 25 %; p < 0.05), and reticular or linear T2 hyperintensity (27 % vs. 0 %; p < 0.05) were more frequently observed in cSCC than in cMM, respectively.Conclusions: cMM predominantly exhibited intratumoral T1 hyperintensity, whereas cSCC predominantly exhibited superficial depression, superficial irregular margins, reticular or linear T2 hyperintensity.