The messenger RNA sequences in growing and resting mouse fibroblasts
The messenger RNA sequences in growing and resting mouse fibroblasts
复制标题
生长和静息小鼠成纤维细胞中的信使 RNA 序列
DOI：
10.1016/0092-8674(75)90010-0
复制
发表时间：
1975
期刊：
影响因子：
64.5
通讯作者：
S. Penman
中科院分区：
文献类型：
--
作者：
Jeffrey G. Williams;S. Penman
已经检查了静息和生长的3 T6细胞中信使RNA中存在的序列。首先，将生长中的3 T6中mRNA的丰度和复杂性类别与其他已建立的细胞系中的那些进行比较。对来自HeLa细胞和三种小鼠成纤维细胞系3 T6、SV-PY-3 T3和L的mRNA测量的总体复杂性在性质上是相似的，并且对应于大约10，000个序列。两个主要丰度类别的相对量和它们的复杂性在三个小鼠成纤维细胞系中似乎是相同的，尽管它们的hlstories不同。HeLa细胞mRNA在两个主要类别的数量和复杂性方面都有显着差异。
The sequences present in messenger RNA in resting and growing 3T6 cells have been examined. First, the abundance and complexity classes of mRNA in growing 3T6 were compared to those in other established cell lines. The overall complexities measured for mRNA from HeLa cells and the three mouse flbroblast llnes, 3T6, SV-PY-3T3, and L, are qualitatively similar and correspond to approximately 10,000 sequences. The relative amount of the two major abundance classes and their complexities appear identical in the three mouse flbroblast lines despite their different hlstories. HeLa cell mRNA is significantly difierent both in the amount and the complexity of the two major classes.