TMJ disorders: future innovations in diagnostics and therapeutics.
TMJ disorders: future innovations in diagnostics and therapeutics.
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DOI：
10.1002/j.0022-0337.2008.72.8.tb04569.x
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发表时间：
2008-08
影响因子：
2.3
通讯作者：
S. Wadhwa;S. Kapila
中科院分区：
文献类型：
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作者：
S. Wadhwa;S. Kapila
由于人们对颞下颌关节 (TMJ) 疾病的病因和发病机制知之甚少，因此很难诊断和治疗。目前所有治疗颞下颌关节疾病的方法基本上都是姑息治疗。只有全面了解颞下颌关节疾病的病因、诱发因素和发病机制，才能做出明确、合理的诊断或治疗。尽管这一领域仍有许多工作要做，但生物医学的新发现以及成像和计算机技术的发展开始为我们提供颞下颌关节疾病诊断和治疗的未来创新愿景。这些进步包括识别和使用局部或全身生物标志物来诊断疾病或监测治疗的改进；使用成像技术进行更早、更灵敏的诊断；以及利用生物医学、仿生学和成像技术来设计和制造生物工程关节。这些进步可能有助于定制和提高我们为颞下颌关节紊乱患者提供的护理质量。
Because their etiologies and pathogenesis are poorly understood, temporomandibular joint (TMJ) diseases are difficult to diagnose and manage. All current approaches to treatments of TMJ diseases are largely palliative. Definitive and rational diagnoses or treatments can only be achieved through a comprehensive understanding of the etiologies, predisposing factors, and pathogenesis of TMJ diseases. While much work remains to be done in this field, novel findings in biomedicine and developments in imaging and computer technologies are beginning to provide us with a vision of future innovations in the diagnostics and therapeutics of TMJ disorders. These advances include the identification and use of local or systemic biomarkers to diagnose disease or monitor improvements in therapy; the use of imaging technologies for earlier and more sensitive diagnostics; and the use of biomedicine, biomimetics, and imaging to design and manufacture bioengineered joints. Such advances are likely to help to customize and enhance the quality of care we provide to patients with TMJ disorders.