Hydrophilic modification of expanded polytetrafluoroethylene (ePTFE) by atmospheric pressure glow discharge (APG) treatment
Hydrophilic modification of expanded polytetrafluoroethylene (ePTFE) by atmospheric pressure glow discharge (APG) treatment
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DOI：
10.1016/j.surfcoat.2005.12.017
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发表时间：
2006-10-05
影响因子：
5.4
通讯作者：
Kogoma, Masuhiro
中科院分区：
文献类型：
--
作者：
Njatawidjaja, Ellyana;Kodama, Makoto;Kogoma, Masuhiro
ePTFE已用于生物医学应用，如人造血管。然而，高度疏水的ePTFE表面的固有性质阻碍了组织向内生长和伤口愈合。应用APG等离子体处理以用AAc或PAA将ePTFE管从疏水性改性为亲水性。将等离子体预处理的ePTFE管浸入AAc或PAA溶液中，然后用氦-APG等离子体处理。FTIR-ATR谱图中出现了一个羰基吸收峰，XPS谱图中F/C降低，O/C增加。处理后的水接触角减小。SEM图像显示ePTFE管的原纤彼此互连以形成组装的原纤束。这些结果表明在ePTFE表面上形成了不溶性聚合的AAc或PAA层。AAc或PAA的聚合开始发生在ePTFE的表面上，然后在多孔结构内继续。PAA对ePTFE的表面改性效果优于AAc。外表面比内表面更亲水。当用PTFE膜包裹ePTFE外管并使用相同的实验方法处理时，观察到内表面上的显著增强的表面改性，特别是使用AAc。AAc更容易附着在ePTFE管的表面，从而增加了ePTFE管内表面的亲水性。(c)2005 Elsevier B. V.保留所有权利。
ePTFE has been used in biomedical applications such as artificial blood vessels. However, the inherent nature of the highly hydrophobic ePTFE surface retards tissue ingrowth and wound healing. APG plasma treatment was applied to modify ePTFE tubes from being hydrophobic to being hydrophilic with AAc or PAA. The plasma-pretreated ePTFE tubes were immersed in AAc or PAA solution, then treated with helium-APG plasma. The spectra of FTIR-ATR adopted the appearance of an absorption peak ascribed to carbonyl group, and XPS showed reduced F/C and increased O/C. The water contact angles after treatment were decreased. An SEM image showed that the fibrils of ePTFE tubes were interconnected with each other to form assembled bundles of fibrils. These results indicated the formation of an insoluble polymerized AAc or PAA layer on the ePTFE surface. Polymerization of AAc or PAA began occurring on the surface of ePTFE and then continued within porous structures. The surfaces of ePTFE were more effectively modified by PAA than AAc. The outer surface was more hydrophilic than the inner surface. When the outer tube of ePTFE was wrapped with PTFE film and processed using the same experimental method, a markedly enhanced surface modification on the inner surface, especially with the use of AAc, was observed. AAc was easier to polymerize on the surface of the ePTFE tube, as a result, the hydrophilicity of the inner surface was increased. (c) 2005 Elsevier B.V. All rights reserved.