The Management of Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With Biologics.
The Management of Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With Biologics.
复制标题
用生物制剂治疗慢性鼻窦炎伴鼻息肉 (CRSwNP)。
DOI：
10.1016/j.jaip.2023.04.054
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Peters,AnjuT
中科院分区：
文献类型：
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作者：
Wautlet,A;Bachert,C;Desrosiers,M;Hellings,PeterW;Peters,AnjuT
慢性鼻窦炎伴鼻息肉影响着全球很大一部分人口。这种疾病与几种慢性疾病有关，对患者的生活质量有重要影响，导致巨大的社会经济负担。近年来，已开发出生物药物，并发现其对治疗慢性鼻窦炎伴鼻息肉有效。本文综述了这些治疗方案及其改善患者预后（包括生活质量）的能力。它还审查了关于患者选择、治疗开始后患者监测、不同生物制剂的比较以及与其他治疗方案（如鼻窦手术）的比较的现有证据。
Chronic rhinosinusitis with nasal polyps affects a significant portion of the worldwide population. This illness is associated with several chronic conditions and has an important impact on patient quality of life, leading to a great societal economic burden. In recent years, biologic medications have been developed and found to be effective in the treatment of chronic rhinosinusitis with nasal polyps. This review focuses on these treatment options and their ability to improve patient outcomes, including quality of life. It also reviews available evidence with regards to patient selection, monitoring of patients after treatment initiation, and comparison of different biologics and with other treatment options such as sinus surgery.