Large-scale parametric survival analysis.
Large-scale parametric survival analysis.
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DOI:
10.1002/sim.5817
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发表时间:
2013-10-15
影响因子:
2
通讯作者:
Burd, Randall S.
中科院分区:
文献类型:
--
作者:
Mittal, Sushil;Madigan, David;Cheng, Jerry Q.;Burd, Randall S.
Survival analysis has been a topic of active statistical research in the past few decades with applications spread across several areas. Traditional applications usually consider data with only small numbers of predictors with a few hundreds or thousands of observations. Recent advances in data acquisition techniques and computation power has led to considerable interest in analyzing very high-dimensional data where the number of predictor variables and the number of observations range between 104 – 106. In this paper, we present a tool for performing large-scale regularized parametric survival analysis using a variant of cyclic coordinate descent method. Through our experiments on two real data sets, we show that application of regularized models to high-dimensional data avoids overfitting and can provide improved predictive performance and calibration over corresponding low-dimensional models.
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