The regulation of MR neuroimaging research: Disentangling the Gordian knot
The regulation of MR neuroimaging research: Disentangling the Gordian knot
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DOI：
10.1177/009885880703300207
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发表时间：
2007-01-01
影响因子：
0.6
通讯作者：
Kulynych, Jennifer J.
中科院分区：
文献类型：
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作者：
Kulynych, Jennifer J.
在典型的大脑磁共振成像（“MRI”）研究中，受试者在被放置在一个大型机器的孔中之前，会被筛选禁忌症，MRI扫描仪包含一个强大的磁铁。当受试者接受一系列短暂的电磁脉冲时，扫描仪会产生脑组织的横截面图像，这些脉冲只能以噪音和振动的形式感知。如果研究方案涉及功能性核磁共振成像（fMRI），一种用于间接测量大脑活动的流行研究技术，设备可能会在扫描过程中提供刺激（声音或图像），但通常研究不涉及侵入性程序，没有身体不适，也没有电离辐射。扫描完成后，MRI数据被传输到研究者的计算机上进行进一步分析，通常与行为测试结果和从受试者或其医疗记录中获得的临床信息相结合。这个过程听起来是良性的，通常也是良性的。但核磁共振扫描仪是一种功能强大的医疗设备，如果操作不慎，可能会造成严重伤害甚至死亡。
In a typical magnetic resonance imaging (“MRI”) study of the brain, subjects are screened for contraindications before being placed in the bore of a large machine, the MRI scanner, which contains a powerful magnet. The scanner produces cross-sectional images of brain tissue as the subjects undergo a series of brief electromagnetic pulses, perceptible only as noise and vibration. If the protocol involves functional MRI (“fMRI”), a popular research technique for obtaining indirect measurements of brain activity, equipment might be used to present stimuli (sounds or pictures) during the scan, but generally the study involves no invasive procedures, no physical discomfort, and no ionizing radiation. Upon completion of the scan, MRI data is transferred to an investigator's computer for further analysis, often in combination with behavioral test results and clinical information obtained from subjects or their medical records.This procedure sounds benign, and usually is. But an MRI scanner is a powerful medical device, capable of causing serious injury or death if operated carelessly.