The spatial spread of schistosomiasis: A multidimensional network model applied to Saint-Louis region, Senegal
The spatial spread of schistosomiasis: A multidimensional network model applied to Saint-Louis region, Senegal
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DOI：
10.1016/j.advwatres.2016.10.012
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发表时间：
2017-10-01
影响因子：
4.7
通讯作者：
Gatto, Marino
中科院分区：
文献类型：
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作者：
Ciddio, Manuela;Mari, Lorenzo;Gatto, Marino
血吸虫病是一种与水有关的寄生虫病，在世界热带和亚热带地区流行，特别是在儿童中造成严重的慢性后果。在这里，我们研究的空间传播这种疾病的网络连接的村庄在塞内加尔河下游流域，在塞内加尔的地方病流行区。分析是通过一个空间上明确的集合种群模型，耦合当地规模的生态流行病学动态与空间机制有关的人的流动性（估计从匿名的移动的电话记录），蜗牛扩散和水文运输的幼虫沿着该地区的主要水体。结果表明，该模型产生的流行病学模式与现场观察一致，并指出空间连通性的疾病传播的关键作用。这些发现强调了考虑不同传播途径的重要性，以便制定在相互联系的人群网络中有效的疾病控制战略。(C)2016作者爱思唯尔有限公司出版
Schistosomiasis is a parasitic, water-related disease that is prevalent in tropical and subtropical areas of the world, causing severe and chronic consequences especially among children. Here we study the spatial spread of this disease within a network of connected villages in the endemic region of the Lower Basin of the Senegal River, in Senegal. The analysis is performed by means of a spatially explicit metapopulation model that couples local-scale eco-epidemiological dynamics with spatial mechanisms related to human mobility (estimated from anonymized mobile phone records), snail dispersal and hydrological transport of schistosome larvae along the main water bodies of the region. Results show that the model produces epidemiological patterns consistent with field observations, and point out the key role of spatial connectivity on the spread of the disease. These findings underline the importance of considering different transport pathways in order to elaborate disease control strategies that can be effective within a network of connected populations. (C) 2016 The Authors. Published by Elsevier Ltd.