BINOCULAR INTERACTIONS IN THE CATS DORSAL LATERAL GENICULATE-NUCLEUS .1. SPATIAL-FREQUENCY ANALYSIS OF RESPONSES OF X-CELLS, Y-CELLS, AND W-CELLS TO NONDOMINANT-EYE STIMULATION
BINOCULAR INTERACTIONS IN THE CATS DORSAL LATERAL GENICULATE-NUCLEUS .1. SPATIAL-FREQUENCY ANALYSIS OF RESPONSES OF X-CELLS, Y-CELLS, AND W-CELLS TO NONDOMINANT-EYE STIMULATION
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DOI：
10.1152/jn.1989.62.2.526
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发表时间：
1989-08-01
影响因子：
2.5
通讯作者：
SPEAR, PD
中科院分区：
文献类型：
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作者：
GUIDO, W;TUMOSA, N;SPEAR, PD
1. 研究了猫背外侧膝状核（LGN） A层和C层的X、Y和W细胞对非优势眼刺激的反应。主要目的是确定不同类型的细胞中非优势眼兴奋和抑制的发生率，并检查对非优势眼的反应的空间频率调谐。2. 198个细胞中，有109个（55%）细胞在非优势眼上显示了显著的反应。观察到四种类型的响应：平均放电率增加（F0激励），平均放电率降低（F0抑制），光栅基频调制增加（F1激励），光栅基频调制减少（F1抑制）。总体而言，29%的细胞表现为抑制反应，24%表现为兴奋反应，2%表现为兴奋和抑制反应，这取决于空间频率和/或谐波响应成分。X、Y和W细胞、中心和中心感受野的细胞、不同感受野偏心率的细胞以及每个LGN层的细胞，兴奋和抑制的相对发生率相似。此外，在层A和A1内，距离层流边界不同距离的细胞的反应相似。3. 空间频率响应函数表明细胞可以通过非主视眼进行带通或低通的空间频率调谐。带通单元倾向于窄调谐（小于或等于1倍频程），而低通单元响应更宽的空间频率范围。这些属性对于X、Y和W单元格是相似的。空间分辨率往往较低（大多数电池小于或等于0.8摄氏度/度），尽管少数电池对测试的最高空间频率（5.4摄氏度/度）有反应。同样，大多数电池的最佳空间频率较低（小于或等于0.2 c/ g）。X和Y细胞的这些特性相似，并且X和Y细胞比W细胞具有更高的最佳空间频率和空间分辨率的趋势较弱。4. 就活动的绝对变化而言，对漂移光栅的响应很弱。然而，被抑制的细胞通常表现出20-60%的活性降低到最佳空间频率，而兴奋的细胞通常表现出40-100%的活性增加。X、Y和W细胞的反应幅度相似。（摘要删节为400字）
1. X, Y, and W cells in the A and C layers of the cat's dorsal lateral geniculate nucleus (LGN) were tested for responses to stimulation of the nondominant eye. The main purpose was to determine the incidence of nondominant-eye excitation and inhibition among different classes of cells and to examine the spatial-frequency tuning of responses to the nondominant eye. 2. Of 198 cells that were tested with drifting sine-wave gratings presented to the nondominant eye, 109 (55%) showed statistically significant responses. Four types of responses were observed: an increase in the mean discharge rate (F0 excitation), a decrease in the mean discharge rate (F0 inhibition), an increased modulation at the fundamental frequency of the grating (F1 excitation), and a decreased modulation at the fundamental frequency of the grating (F1 inhibition). Overall, 29% of the cells responded with inhibition, 24% responded with excitation, and 2% showed both excitation and inhibition, depending upon the spatial frequency and/or the harmonic response component. The relative incidence of excitation and inhibition was similar for X, Y, and W cells, for cells with on-center and off-center receptive fields, for cells with different receptive-field eccentricities, and for cells in each LGN layer. In addition, within layers A and A1, responses were similar for cells at different distances from the laminar borders. 3. Spatial-frequency response functions indicated that cells could have band-pass or low-pass spatial-frequency tuning through the nondominant eye. Band-pass cells tended to be narrowly tuned (less than or equal to 1 octave), and low-pass cells responded to a broader range of spatial frequencies. These properties were similar for X, Y, and W cells. Spatial resolution tended to be low (less than or equal to 0.8 c/deg for most cells), although a few cells responded to the highest spatial frequency tested (5.4 c/deg). Likewise, optimal spatial frequency was low (less than or equal to 0.2 c/deg) for most cells. These properties were similar for X and Y cells, and there was a weak tendency for X and Y cells to have higher optimal spatial frequencies and spatial resolutions than W cells. 4. In terms of absolute change in activity, responses to drifting gratings were weak. However, cells that were inhibited generally showed 20-60% decreases in activity to the optimal spatial frequency, and cells that were excited generally showed 40-100% increases. Response amplitudes were similar for X, Y, and W cells.(ABSTRACT TRUNCATED AT 400 WORDS)