Brief communication: cortical remodeling data are affected by sampling location.
Brief communication: cortical remodeling data are affected by sampling location.
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简要交流：皮质重塑数据受采样位置影响。
DOI：
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发表时间：
1995
影响因子：
2.8
通讯作者：
James Chiang
中科院分区：
文献类型：
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作者：
S. Pfeiffer;R. Lazenby;James Chiang
有人认为，技术估计成年人死亡年龄的皮质组织学是有害的采样位置的影响。本研究使用9个完整的股骨中段横截面来测试采样部位对标准组织学变量（重塑骨百分比）测量的影响。评价了四个解剖学定义位置（前、后、内侧、外侧）和四个机械定义位置（最大和最小面积矩）的周向骨膜区域。从骨膜表面向骨内膜表面偏离的位置也进行了比较。显着差异，发现位置和外地安置。解剖轴表现出更大的变异性比机械轴，特别是前位置，死亡年龄估计技术的标准采样点。更多的骨内膜区域倾向于显示出重塑骨百分比水平升高。这项研究表明，周向和径向采样位置是重要的考虑因素，在推导和应用基于皮质重塑的预测方程。
It has been argued that techniques for estimating adult age-at-death from cortical histology are deleteriously affected by sampling location. This study uses nine complete femoral midshaft cross-sections to test the effect of sampling site on measurement of a standard histological variable, percent remodeled bone. Circumferential periosteal fields from four anatomically defined locations (anterior, posterior, medial, lateral) and four mechanically defined locations (maximum and minimum moments of area) were evaluated. Locations deviating from the periosteal surface toward the endosteal surface were also compared. Significant differences were found for both location and field placement. The anatomical axes exhibited greater variability than the mechanical axes, in particular the anterior location, a standard sampling site for age-at-death estimation techniques. More endosteal fields tended to show elevated levels of percent remodeled bone. This study demonstrates that circumferential and radial sampling locations are important considerations in deriving and applying predictive equations based on cortical remodeling.