Protein supplementation before and after resistance training in older men
Protein supplementation before and after resistance training in older men
复制标题
DOI：
10.1007/s00421-006-0223-8
复制
发表时间：
2006-07-01
影响因子：
3
通讯作者：
Zello, Gordon A.
中科院分区：
文献类型：
--
作者：
Candow, Darren G.;Chilibeck, Philip D.;Zello, Gordon A.
我们确定了老年男性（59-76 岁）在阻力训练（RT；12 周）之前（PRO-B）和之后（PRO-A）补充蛋白质的效果，以及与年轻男性（18-40 岁）相比，这是否可以减少肌肉质量和力量的缺陷。老年男性被随机分配至 PRO-B（放疗前 0.3 g/kg 蛋白质 + 放疗后安慰剂，n=9）、PRO-A（放疗前安慰剂 + 放疗后蛋白质，n=10）或 PLA（放疗前后安慰剂，n=10）。在 RT 之前和之后测量瘦组织质量、肘部、膝部和踝部屈肌和伸肌的肌肉厚度以及腿部和卧推力量，并与年轻受试者 (n=22-60) 的数据库进行比较。放疗前后还测量了肌原纤维蛋白降解（3-甲基组氨酸）和骨吸收（交联 N-端肽）。瘦肉组织质量、肌肉厚度（踝背屈肌除外）和力量随着训练而增加（P < 0.05），组间差异不大。 3-甲基组氨酸或交联 N-端肽没有变化。 RT 之前，除肘部伸肌厚度外，老年组的所有指标均低于年轻组 (P < 0.05)。训练后，肘屈肌和踝背屈肌的肌肉厚度以及腿部按压力量与年轻人相比不再有差异，而老年人的肘伸肌厚度更大（P < 0.05）。训练前后补充蛋白质对老年男性的肌肉质量和力量没有影响。与年轻男性相比，RT 足以克服老年人肘屈肌和踝背屈肌的肌肉尺寸以及腿部按压力量的缺陷。
We determined the effects of protein supplementation immediately before (PRO-B) and after (PRO-A) resistance training (RT; 12 weeks) in older men (59-76 years), and whether this reduces deficits in muscle mass and strength compared to younger men (18-40 years). Older men were randomized to PRO-B (0.3 g/kg protein before RT + placebo after RT, n=9), PRO-A (placebo before + protein after RT, n=10), or PLA (placebo before and after RT, n=10). Lean tissue mass, muscle thickness of the elbow, knee, and ankle flexors and extensors, and leg and bench press strength were measured before and after RT and compared to databases of younger subjects (n=22-60). Myofibrillar protein degradation (3-methylhistidine) and bone resorption (cross-linked N-telopeptides) were also measured before and after RT. Lean tissue mass, muscle thickness (except ankle dorsi flexors), and strength increased with training (P < 0.05), with little difference between groups. There were no changes in 3-methylhistidine or cross-linked N-telopeptides. Before RT, all measures were lower in the older compared to younger groups (P < 0.05), except for elbow extensor muscle thickness. Following training, muscle thickness of the elbow flexors and ankle dorsi flexors and leg press strength were no longer different than the young, and elbow extensor muscle thickness was greater in the old men (P < 0.05). Supplementation with protein before or after training has no effect on muscle mass and strength in older men. RT was sufficient to overcome deficits in muscle size of the elbow flexors and ankle dorsi flexors and leg press strength in older compared to younger men.