Synthesis of (+)-9a-epi-Stemoamide via DBU-Catalyzed Michael Addition of Nitroalkane
Synthesis of (+)-9a-epi-Stemoamide via DBU-Catalyzed Michael Addition of Nitroalkane
复制标题
DBU 催化硝基烷迈克尔加成合成 ( )-9a-epi-Stemoamide
DOI：
10.1055/s-0029-1217558
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发表时间：
2009-08-13
期刊：
影响因子：
2
通讯作者：
Zhai, Hongbin
中科院分区：
文献类型：
--
作者：
Gao, Peng;Tong, Zhaolong;Zhai, Hongbin
We describe a practical synthesis of (+)-9a-epi-stemoamide, which has been achieved in six steps from a,p-unsaturated gamma-butyrolactone. The main features of the current approach include a DBU-catalyzed Michael addition of nitroalkane and a reductive lactamization of nitro esters.
