CONTRALATERAL NEGLECT AFTER UNILATERAL DORSOMEDIAL PREFRONTAL LESIONS IN RATS

CONTRALATERAL NEGLECT AFTER UNILATERAL DORSOMEDIAL PREFRONTAL LESIONS IN RATS
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DOI:
10.1016/0006-8993(74)90649-0
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发表时间:
1974-01-01
期刊:
影响因子:
2.9
通讯作者:
BOZEK, T
BOZEK, T
中科院分区:
医学3区
文献类型:
--
作者:
COWEY, A;BOZEK, T

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在Y迷宫中确定大鼠的侧向偏好后,单侧切除背内侧或背外侧前额叶皮质。后一种手术对选择行为没有影响,而前一种手术后转向病变对侧的次数显着减少。这些结果与最近的解剖学实验有关,这些实验表明,大鼠的背内侧前额叶皮质可能与猴子的额叶视野同源,切除一侧前额皮质会导致对侧忽略。
After determining the side preferences of rats in a Y-maze either the dorsomedial or dorsolateral prefrontal cortex was removed unilaterally. The latter operation had no effect on choice behaviour whereas the former was followed by a significant reduction of turns to the side contralateral to the lesion. The results are discussed in relation to recent anatomical experiments which indicate that the dorsomedial prefrontal cortex in the rat may be homologous to the frontal eye-fields of monkeys, unilateral removal of which causes a contralateral neglect.