How could we end the epidemic of cardio-metabolic diseases?
How could we end the epidemic of cardio-metabolic diseases?
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我们如何才能结束心脏代谢疾病的流行？
DOI：
10.3760/cma.j.issn.1000-6699.2017.06.001
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发表时间：
2017
影响因子：
--
通讯作者：
Fangchao Liu
中科院分区：
文献类型：
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作者：
Xiaochen Lin;Fangchao Liu
在全球范围内，慢性病患者现在消耗了所有医疗资源的80%以上。与这一令人沮丧的预测相反，数十年的流行病学工作表明，80%-90%的心血管疾病可以通过生活方式和饮食干预来预防。我们如何才能调和这种对人类心血管健康未来的对立观点？在此，我们回顾了可用的证据来源，可以用来回答这些具有挑战性的问题，如何和为什么。特别是，我们提出，结合6P（预测，精确，个性化，预防，人口和政策）-3G（良好的食物，良好的环境和良好的行为）-4I（解释，整合，实施和创新）的分析框架将使我们能够集中资源开发多层次的方法，以改善人口健康。(Chin内分泌代谢杂志，2017，33：453-459）
关键词：
代谢性疾病;疾病预防与控制;生活方式干预;基因-环境交互作用
Globally, individuals with chronic diseases now consume over 80% of all healthcare resources. Set against this depressing projection is decades of epidemiologic work demonstrating that 80%-90% of cardiovascular disease can be prevented via lifestyle and dietary interventions. How can we reconcile such contrasting views toward the future of cardiovascular health in human populations? Herein, we review available sources of evidence that can be used to answer these challenging questions of how and why. In particular, we submit that analytical framework incorporating the 6P (prediction, precision, personalization, prevention, population, and policy)-3G (good food, good environment, and good behavior)-4I (interpretation, integration, implementation, and innovation) will allow us to focus resource towards the development of multi-level approaches for the betterment of population health. (Chin J Endocrinol Metab, 2017, 33: 453-459)
Key words:
Cardio-metabolic diseases; Disease prevention and control; Lifestyle intervention; Gene-environment interactions