Relationship of trait impulsivity with clinical presentation in euthymic bipolar disorder patients
Relationship of trait impulsivity with clinical presentation in euthymic bipolar disorder patients
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DOI：
10.1016/j.psychres.2011.06.010
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发表时间：
2011-12-30
影响因子：
11.3
通讯作者：
Caykoylu, Ali
中科院分区：
文献类型：
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作者：
Ekinci, Okan;Albayrak, Yakup;Caykoylu, Ali
本研究旨在探讨双相情感障碍患者的特质冲动性，并探讨冲动性与疾病临床表现之间的可能联系。诊断基于DSM-IV的结构化临床访谈。对71例经Young躁狂量表和汉密尔顿抑郁量表评定为心境正常的双相情感障碍患者的社会人口学和临床特征进行了记录。采用Barratt冲动量表（BIS）和气质与性格量表中的冲动分量表评价其特质冲动性，并与50名年龄和性别匹配的健康对照组和不同临床特征的患者进行比较。双相患者的所有BIS-11子量表评分均高于对照组。没有教育和年龄的影响。BIS-11评分升高与主要抑郁极性、病程延长、精神病性情绪发作史和自杀企图相关。当年龄、性别和教育被考虑在内时，这些关系仍然存在。这些结果表明，在考虑常见的混杂因素后，双相情感障碍患者的特质样冲动性显著高于非双相情感障碍对照组，并且可能因不同的临床表现而异。(C)2011爱思唯尔爱尔兰有限公司保留所有权利。
The purpose of this study was to examine trait impulsivity in patients with bipolar disorder and explore the possible connections between impulsivity and clinical presentation of the illness. Diagnoses were based on the Structured Clinical Interview for DSM-IV. The sociodemographic and clinical properties of 71 patients with bipolar disorder, who were euthymic according to Young Mania Rating Scale and Hamilton Depression Scale scores, were recorded. Their trait impulsivity was evaluated by using the Barratt Impulsiveness Scale (BIS) and impulsivity subscale of the Temperament and Character Inventory, and the results were compared with 50 age- and sex-matched healthy controls and among patients with different clinical properties. All BIS-11 subscale scores were higher in bipolar than in comparison subjects. There were no effects of education and age. Elevated BIS-11 scores were associated with predominant depressive polarity, longer duration of illness and a history of psychotic mood episodes and suicide attempts. These relationships persisted when age, gender, and education were taken into account. These results show that after accounting for common confounding factors, trait-like impulsivity was substantially higher in subjects with bipolar disorder than in nonbipolar comparison subjects and may vary according to different clinical presentations. (C) 2011 Elsevier Ireland Ltd. All rights reserved.