Pediatric brain injury: can DTI scalars predict functional outcome?
Pediatric brain injury: can DTI scalars predict functional outcome?
复制标题
DOI：
10.1007/s00247-012-2481-4
复制
发表时间：
2013-01-01
影响因子：
2.3
通讯作者：
Barkovich, A. James
中科院分区：
文献类型：
--
作者：
Xu, Duan;Mukherjee, Pratik;Barkovich, A. James
扩散成像通过推断微观结构的变化，即细胞膜、髓鞘和其他抑制水扩散的结构，已经在各种疾病的临床诊断中取得了重大进展。本文综述了近年来在使用扩散参数预测功能的结果。在文献中的研究仅使用标量参数的扩散测量，如表观扩散系数（ADC）和分数各向异性（FA），进行了总结。还简要讨论了其他更复杂的数学模型和后处理用途。
Diffusion imaging has made significant inroads into the clinical diagnosis of a variety of diseases by inferring changes in microstructure, namely cell membranes, myelin sheath and other structures that inhibit water diffusion. This review discusses recent progress in the use of diffusion parameters in predicting functional outcome. Studies in the literature using only scalar parameters from diffusion measurements, such as apparent diffusion coefficient (ADC) and fractional anisotropy (FA), are summarized. Other more complex mathematical models and post-processing uses are also discussed briefly.