DRINKING AND ITS RELATION TO SMOKING, BP, BLOOD-LIPIDS, AND URIC-ACID - THE FRAMINGHAM-STUDY
DRINKING AND ITS RELATION TO SMOKING, BP, BLOOD-LIPIDS, AND URIC-ACID - THE FRAMINGHAM-STUDY
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DOI：
10.1001/archinte.143.7.1366
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发表时间：
1983-01-01
影响因子：
--
通讯作者：
KANNEL, WB
中科院分区：
文献类型：
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作者：
GORDON, T;KANNEL, WB
对5209名男性和女性的饮酒习惯和其他特征进行了20年的观察。平均饮酒量上升了63%。妇女和年轻人的增长率更高。血清尿酸和磷脂浓度较高，在较高水平的酒精消费。0-12和100-400 Svedberg U的脂蛋白水平与男性饮酒呈正相关，但与女性饮酒呈负相关。不饮酒者的血压[BP]高于轻度饮酒者，但饮酒者的血压在较高的消费水平下更高。虽然吸烟者的血压比不吸烟者低，但这似乎是由于他们的体重较轻。在随访期间增加饮酒量的人的血清磷脂和尿酸水平、血压和体重相对于这些变量的平均变化平均增加较小。
Drinking habits and other characteristics were observed for 20 yr in a cohort of 5209 Framingham men and women. The average amount of alcohol consumed rose 63%. The percent increase was greater for women and greater for younger persons. Serum uric acid and phospholipid concentrations were higher at higher levels of alcohol consumption. Lipoprotein levels of 0-12 and 100-400 Svedberg U were positively associated with alcohol consumption in men but negatively associated with alcohol consumption in women. Blood pressure [BP] was higher in nondrinkers than light drinkers, but among drinkers BP was higher at higher consumption levels. While cigarette smokers had lower BP than nonsmokers, this seemed to be due to their lower weight. Persons who increased their alcohol consumption during follow-up had a small mean increase in serum phospholipid and uric acid levels, BP and weight relative to the average changes for these variables.