Long-term progressive motor skill training enhances corticospinal excitability for the ipsilateral hemisphere and motor performance of the untrained hand
Long-term progressive motor skill training enhances corticospinal excitability for the ipsilateral hemisphere and motor performance of the untrained hand
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DOI：
10.1111/ejn.13409
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发表时间：
2017-06-01
影响因子：
3.4
通讯作者：
Lundbye-Jensen, Jesper
中科院分区：
文献类型：
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作者：
Christiansen, Lasse;Larsen, Malte Nejst;Lundbye-Jensen, Jesper
众所周知，单侧运动练习可以提高未受过训练的另一只手的表现。在这里，我们检验了一种假设，即在长期的右手技能训练中，逐渐增加任务难度可以提高未受过训练的左手的表现和皮质运动兴奋性。受试者练习右手数字V的视觉运动追踪任务6周，任务难度递增(PT)或无进展(NPT)。应用经颅磁刺激(TMS)对左侧小指展肌(ADM)同侧初级运动皮质(IM1)区进行刺激后，根据静息运动阈值(RMT)和募集曲线参数评价皮质脊髓兴奋性(CSE)。训练6周后，PT使左手运动能力显著提高(63+/-18%，P
It is well established that unilateral motor practice can lead to increased performance in the opposite non-trained hand. Here, we test the hypothesis that progressively increasing task difficulty during long-term skill training with the dominant right hand increase performance and corticomotor excitability of the left non-trained hand. Subjects practiced a visuomotor tracking task engaging right digit V for 6weeks with either progressively increasing task difficulty (PT) or no progression (NPT). Corticospinal excitability (CSE) was evaluated from the resting motor threshold (rMT) and recruitment curve parameters following application of transcranial magnetic stimulation (TMS) to the ipsilateral primary motor cortex (iM1) hotspot of the left abductor digiti minimi muscle (ADM). PT led to significant improvements in left-hand motor performance immediately after 6weeks of training (63 +/- 18%, P