Brain activity of women is more fractal than men
Brain activity of women is more fractal than men
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DOI：
10.1016/j.neulet.2012.12.043
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发表时间：
2013-02-22
影响因子：
2.5
通讯作者：
Sajedi, Firoozeh
中科院分区：
文献类型：
--
作者：
Ahmadi, Khodabakhsh;Ahmadlou, Mehran;Sajedi, Firoozeh
研究大脑的性别差异具有科学和临床意义，因为了解这种差异可能有助于改善神经精神疾病的性别特异性治疗。由于大脑是一个高度复杂的系统，从非线性动力学的角度研究其活动是至关重要的。然而，很少有研究基于大脑的动态特征来调查性别差异。分形维数（FD）是脑动力学的一个关键特征，它表明神经元区域的功能或相互作用的复杂程度，并在从完全确定性到完全随机的范围内量化相关的脑过程。本研究通过比较34名女性和34名男性健康成人闭眼静息状态下的头皮脑电图分形维数，探讨脑动力学的性别差异。结果显示，除了侧叶和枕叶外，女性的FDs在所有脑区都明显高于男性。这表明女性的大脑动态比男性更复杂。逻辑回归和增强概率神经网络基于FDs区分性别群体的准确率分别高达87.8%和93.1%，也证实了脑活动复杂性的性别差异很大。结果表明，δ、α和β波段是对大脑复杂性的性别差异贡献最大的频段。此外，侧化分析表明，女性复杂性的左侧化程度高于男性。2013爱思唯尔爱尔兰有限公司版权所有。
Investigating gender differences of the brain is of both scientific and clinical importance, as understanding such differences may be helpful for improving gender specific treatments of neuropsychiatric disorders. As brain is a highly complex system, it is crucial to investigate its activity in terms of nonlinear dynamics. However, there are few studies that investigated gender differences based on dynamical characteristics of the brain. Fractal dimension (FD) is a key characteristic of the brain dynamics which indicates the level of complexity on which the neuronal regions function or interact and quantifies the associated brain processes on a scale ranging from fully deterministic to fully random. This study investigates the gender differences of brain dynamics, comparing fractal dimension of scalp EEGs (in eyes-closed resting state) of 34 female and 34 male healthy adults. The results showed significantly greater FDs in females compared to males in all brain regions except in lateral and occipital lobes. This indicates a higher complexity of the brain dynamics in females relative to males. The high accuracies of 87.8% and 93.1% obtained by logistic regression and enhanced probabilistic neural network, respectively, in discriminating between the gender groups based on the FDs also confirmed the great gender differences of complexity of brain activities. The results showed that delta, alpha, and beta bands are the frequency bands that contribute most to the gender differences in brain complexity. Furthermore, the lateralization analysis showed the leftward lateralization of complexity in females is greater than in males. (C) 2013 Elsevier Ireland Ltd. All rights reserved.